SCHEMBL514973

SCHEMBL514973

[CH2]OCOC(=O)c1ccc(N)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.61
CYP1A2 P05177 3/20 0.61
CYP3A4 P08684 3/20 0.61
MAOA P21397 2/20 0.61
TSHR P16473 2/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
PDE4D Q08499 1/20 0.54
PHLPP2 Q6ZVD8 1/20 0.53
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
MAPT P10636 2/20 0.51
ALDH1A1 P00352 1/20 0.51
CYP2D6 P10635 2/20 0.50
HTR3A P46098 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50
BLM P54132 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
SCN1A P35498 2/20 0.47
SCN2A Q99250 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2946645 0.88 LMNA (0.70) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL514606 0.81 TPMT (0.43) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL513611 0.81 TDP1 (0.53) LMNACYP1A2CYP3A4MAOANPC1
SCHEMBL514974 0.81 LMNA (0.67) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL514539 0.80 TDP1 (0.59) LMNACYP1A2TSHRCYP2C9CYP2C19
SCHEMBL291777 0.79 NPC1 (0.73) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL514455 0.77 LMNA (0.55) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL11019107 0.77 LMNA (0.64) LMNACYP1A2CYP3A4MAOATSHR
Benzocaine SCHEMBL25100 0.76 LMNA (1.00) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL48450 0.76 LMNA (0.79) LMNACYP1A2CYP3A4MAOATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 LMNA 4076/4885CYP1A2 1189/4885CYP3A4 2169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.