Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144598 | 0.84 | KDM2B (0.42) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL5141474 | 0.81 | HSD11B1 (0.45) | KMT2AMEN1ALDH1A1GBA1HSD11B1 | |
| SCHEMBL5142690 | 0.78 | HTT (0.48) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL4988434 | 0.77 | KMT2A (0.54) | KMT2AMEN1NR3C1LMNAHTT | |
| SCHEMBL4988430 | 0.77 | KMT2A (0.48) | KMT2AMEN1NR3C1LMNAHTT | |
| SCHEMBL5141447 | 0.76 | L3MBTL1 (0.40) | KMT2AMEN1LMNAHTTALOX15 | |
| SCHEMBL5142653 | 0.76 | MEN1 (0.43) | KMT2AMEN1GBA1 | |
| SCHEMBL5141465 | 0.76 | EPHX2 (0.40) | KMT2AMEN1ALDH1A1HSD11B1L3MBTL1 | |
| SCHEMBL5142770 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1HTTTSHRALDH1A1 | |
| SCHEMBL5141453 | 0.75 | L3MBTL1 (0.42) | KMT2AMEN1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297700-B2 | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof | RENOVIS, INC. (US) | 2007-11-20 | — | — | US | claimed |