Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864704 | 0.80 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8584570 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL11286647 | 0.79 | TSHR (0.38) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL3457363 | 0.77 | TSHR (0.36) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL10768836 | 0.77 | TSHR (0.36) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL6239457 | 0.77 | TSHR (0.36) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL186681 | 0.77 | TSHR (0.36) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL28144948 | 0.76 | MMP1 (0.33) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL11552683 | 0.75 | TSHR (0.35) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL31193687 | 0.75 | TSHR (0.35) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999758-B2 | Inhibitors of the YAP/TAZ-TEAD interaction and their use in the treatment of cancer | INVENTIVA (FR) | 2024-06-04 | — | — | US | disclosed |
| CN-114958091-B | recording method and ink jet recording apparatus | 精工爱普生株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-117757303-A | Inkjet ink composition and recording method | 精工爱普生株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-117341373-A | Recording method and recording device | 精工爱普生株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-114316681-B | Ink container and ink composition | 精工爱普生株式会社 | 2024-01-02 | — | — | CN | disclosed |
| CN-114683697-B | Recording method and recording device | 精工爱普生株式会社 | 2023-11-14 | — | — | CN | disclosed |
| CN-114058213-B | White ink composition and ink jet recording method | 精工爱普生株式会社 | 2023-05-12 | — | — | CN | disclosed |
| CN-112874159-B | Ink jet recording method and ink jet recording apparatus | 精工爱普生株式会社 | 2023-05-12 | — | — | CN | disclosed |
| CN-110949030-B | Ink jet recording method and ink jet recording apparatus | 精工爱普生株式会社 | 2023-05-02 | — | — | CN | disclosed |
| CN-115612349-A | Inkjet ink composition and recording method | 精工爱普生株式会社 | 2023-01-17 | — | — | CN | disclosed |
| WO-2004040002-A2 | ARYL PHOSPHATE DERIVATIVES OF d4T HAVING ACTIVITY AGAINST RESISTANT HIV STRAINS | PARKER HUGHES INSTITUTE (US) | 2004-05-13 | — | — | WO | disclosed |
| US-20040087549-A1 | Aryl phosphate derivatives of d4T having activity against resistant HIV strains | UCKUN, FATIH M. | 2004-05-06 | — | — | US | disclosed |
| US-20040077607-A1 | Aryl phosphate derivatives of d4T with potent anti-viral activity against hemorrhagic fever viruses | PARKER HUGHES INSTITUTE | 2004-04-22 | — | — | US | disclosed |
| US-20030236218-A1 | Aryl phosphate derivatives of d4T with selective activity against adenovirus and HIV | PARKER HUGHES INSTITUTE | 2003-12-25 | — | — | US | disclosed |
| WO-2003105863-A1 | ARYL PHOSPHATE DERIVATIVES WITH SELECTIVE ACTIVITY AGAINST ADENOVIRUS AND HIV | PARKER HUGHES INSTITUTE (US) | 2003-12-24 | — | — | WO | disclosed |
| US-6482805-B2 | AZT derivatives exhibiting spermicidal and anti-viral activity | PARKER HUGHES INSTITUTE | 2002-11-19 | — | — | US | disclosed |
| US-6465641-B1 | METHOD INCLUDES CONTACTING PHOSPHOROUS OXYCHLORIDE WITH A HALOPHENYL MOIETY FOLLOWED BY CONTACTING THE RESULTING HALOPHENYLPHOSPHORODICHLORIDATE WITH A CARBOXY-PROTECTED AMINO ACID AND FINALLY CONTACTING THE RESULTING HALOPHENYLCARBOXY | PARKER HUGHES INSTITUTE | 2002-10-15 | — | — | US | disclosed |
| US-20020137726-A1 | Aryl phosphate derivatives of D4T with potent anti-viral activity | PARKER HUGHES INSTITUTE | 2002-09-26 | — | — | US | disclosed |
| US-20020025922-A1 | AZT derivatives exhibiting spermicidal and anti-viral activity | UCKUN, FATIH M. | 2002-02-28 | — | — | US | disclosed |
| WO-2000056750-A1 | ONE POT SYNTHESIS OF 5'-HYDROXY PHOSPHORYLATED NUCLEOSIDE DERIVATIVES, AND COMPOUNDS FORMED THEREBY | PARKER HUGHES INSTITUTE (US) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087549-A1 | Aryl phosphate derivatives of d4T having activity against resistant HIV strains | TYMP, PNP, APRT | ALDH1A1 1280/4885TSHR 3591/4885CYP2D6 587/4885 |
| US-11999758-B2 | Inhibitors of the YAP/TAZ-TEAD interaction and their use in the treatment of cancer | YAP1, TEAD2, YES1 | ALDH1A1 2232/4885TSHR 408/4885CYP2D6 2280/4885 |
| US-20040077607-A1 | Aryl phosphate derivatives of d4T with potent anti-viral activity against hemorrhagic fever viruses | PNP, GNPAT, AASDHPPT | ALDH1A1 1584/4885TSHR 2806/4885CYP2D6 810/4885 |
| US-20020025922-A1 | AZT derivatives exhibiting spermicidal and anti-viral activity | TYMP, DUT, UNG | ALDH1A1 919/4885TSHR 3274/4885CYP2D6 959/4885 |
| US-20020137726-A1 | Aryl phosphate derivatives of D4T with potent anti-viral activity | TYMP, PNP, GART | ALDH1A1 1996/4885TSHR 2983/4885CYP2D6 257/4885 |
| US-20030236218-A1 | Aryl phosphate derivatives of d4T with selective activity against adenovirus and HIV | APRT, AASDHPPT, GNPAT | ALDH1A1 1540/4885TSHR 3543/4885CYP2D6 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.