Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331475 | 0.99 | ALDH1A1 (0.65) | LMNAALDH1A1MAPK1TSHRTP53 | |
| SCHEMBL7205837 | 0.99 | ALDH1A1 (0.65) | LMNAALDH1A1MAPK1TSHRTP53 | |
| SCHEMBL14877495 | 0.99 | ALDH1A1 (0.65) | LMNAALDH1A1MAPK1TSHRTP53 | |
| SCHEMBL1123572 | 0.99 | ALDH1A1 (0.65) | LMNAALDH1A1MAPK1TSHRTP53 | |
| SCHEMBL502564 | 0.96 | LMNA (0.67) | LMNAALDH1A1MAPK1TSHRTP53 | |
| SCHEMBL15797630 | 0.91 | LMNA (0.57) | LMNAALDH1A1MAPK1TSHRTDP1 | |
| SCHEMBL6344467 | 0.91 | ALDH1A1 (0.56) | LMNAALDH1A1MAPK1TSHRTP53 | |
| SCHEMBL13236533 | 0.91 | ALDH1A1 (0.56) | LMNAALDH1A1MAPK1TSHRTP53 | |
| SCHEMBL6344463 | 0.91 | ALDH1A1 (0.56) | LMNAALDH1A1MAPK1TSHRTP53 | |
| Etocrylene SCHEMBL9180144 | 0.90 | ALDH1A1 (0.67) | LMNAALDH1A1MAPK1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008184463-A | SYNTHESIS OF NEW ULTRAVIOLET LIGHT ABSORBER BY DEHYDROCHLORINATING CONDENSATION BETWEEN 2-CYANO-3,3-DIPHENYLACRYLOYL CHLORIDE AND HYDROXY GROUP-CONTAINING SEVERAL KINDS OF COMPOUNDS | SHIPRO KASEI KAISHA LTD | 2008-08-14 | — | — | JP | disclosed |