Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145077 | 0.86 | KMT2A (0.49) | KMT2AALDH1A1RXRARXRBRXRG | |
| Hydrochloric Acid SCHEMBL5145668 | 0.85 | KMT2A (0.47) | KMT2AALDH1A1RXRARXRBRXRG | |
| SCHEMBL5167967 | 0.84 | MAPT (0.48) | KMT2AALDH1A1BCL2L1MAPTMAPK1 | |
| SCHEMBL5143539 | 0.81 | BCL2L1 (0.53) | KMT2AALDH1A1RXRARXRBRXRG | |
| SCHEMBL2567410 | 0.76 | ALDH1A1 (0.53) | PDK1KMT2AALDH1A1PDE4BTSHR | |
| SCHEMBL7353148 | 0.76 | PDE4B (0.54) | PDK1KMT2AALDH1A1PDE4BTSHR | |
| SCHEMBL5888699 | 0.76 | TYR (0.40) | MDM2ALDH1A1HDAC8MAPT | |
| SCHEMBL340676 | 0.75 | TSHR (0.43) | PDK1KMT2AALDH1A1PARP10PDE4B | |
| SCHEMBL2536671 | 0.74 | TSHR (0.47) | PDK1KMT2AALDH1A1KCNQ3KCNQ2 | |
| SCHEMBL1014238 | 0.74 | RORC (0.56) | PDK1KMT2AKCNQ3KCNQ2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123592-A1 | Terephthalamide peptidomimetic compounds and methods | YALE UNIVERSITY (US) | 2007-05-31 | — | — | US | disclosed |
| EP-1723100-A4 | TEREPHTHALAMIDE PEPTIDOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2007-04-04 | — | — | EP | disclosed |
| EP-1723100-A2 | TEREPHTHALAMIDE PEPTIDOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005079541-A2 | TEREPHTHALAMIDE PEPTIDOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123592-A1 | Terephthalamide peptidomimetic compounds and methods | CRHBP, ANPEP, DNPEP | PDK1 4698/4885MDM2 1413/4885KMT2A 3077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.