Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145964 | 0.93 | NPC1 (0.43) | NPC1RAB9APOLBMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL10610834 | 0.85 | MAPK1 (0.41) | NPC1RAB9APOLBMAPTTDP1 | |
| SCHEMBL873380 | 0.84 | ALDH1A1 (0.48) | NPC1RAB9APOLBMAPTTDP1 | |
| SCHEMBL26697028 | 0.83 | LMNA (0.49) | NPC1RAB9APOLBMAPTTDP1 | |
| SCHEMBL16672886 | 0.81 | CYP1A2 (0.48) | NPC1RAB9ATDP1ALDH1A1HDAC3 | |
| SCHEMBL3504292 | 0.80 | NAAA (0.44) | NPC1RAB9APOLBMAPTTDP1 | |
| SCHEMBL3834968 | 0.80 | SIGMAR1 (0.46) | NPC1RAB9APOLBMAPTSSTR4 | |
| SCHEMBL29023306 | 0.79 | ALDH1A1 (0.44) | NPC1RAB9APOLBMAPTTDP1 | |
| SCHEMBL8982552 | 0.79 | NAAA (0.44) | NPC1RAB9APOLBMAPTSSTR4 | |
| SCHEMBL13269168 | 0.78 | PRSS1 (0.39) | TDP1NAAAALDH1A1ATMKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240552-B1 | WATER-PROCESSABLE PHOTORESIST COMPOSITIONS | INTELLECTUAL VENTURES HOLDING 40 LLC (US) | 2012-09-19 | — | — | EP | disclosed |
| EP-1240552-A4 | WATER-PROCESSABLE PHOTORESIST COMPOSITIONS | UNIV TEXAS (US) | 2007-10-17 | — | — | EP | disclosed |
| US-6849649-B2 | N-phenpropylcyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase | PFIZER INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-20040106611-A1 | N-phenpropylcyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase | PFIZER INC | 2004-06-03 | — | — | US | disclosed |
| US-6660756-B2 | N-phenpropylcyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase | PFIZER INC. | 2003-12-09 | — | — | US | disclosed |
| US-20030105132-A1 | N-phenpropylcuclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase | PFIZER INC. | 2003-06-05 | — | — | US | disclosed |
| EP-1240552-A1 | WATER-PROCESSABLE PHOTORESIST COMPOSITIONS | Board of Regents, The University of Texas System (US) | 2002-09-18 | — | — | EP | disclosed |
| US-6399273-B1 | Water-processable photoresist compositions | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM | 2002-06-04 | — | — | US | disclosed |
| WO-2001013179-A1 | WATER-PROCESSABLE PHOTORESIST COMPOSITIONS | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2001-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105132-A1 | N-phenpropylcuclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase | PREP, ENGASE, ENPEP | NPC1 1552/4885RAB9A 3887/4885POLB 3308/4885 |
| US-20040106611-A1 | N-phenpropylcyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase | PREP, ENGASE, ENPEP | NPC1 1508/4885RAB9A 3818/4885POLB 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.