Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PRKDC | P78527 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635784 | 0.90 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL10734426 | 0.85 | POLB (0.47) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL38661111 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL20123251 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL3751505 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL20661182 | 0.83 | PRKDC (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL5144957 | 0.83 | ERN1 (0.59) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL11999809 | 0.83 | PRKDC (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL14430664 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL31628927 | 0.78 | PRKDC (0.48) | ALDH1A1KDM4ETSHRTDP1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070203080-A1 | New Drug Delivery System for Crossing the Blood Brain Barrier | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203080-A1 | New Drug Delivery System for Crossing the Blood Brain Barrier | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203080-A1 | New Drug Delivery System for Crossing the Blood Brain Barrier | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-30 | — | — | US | disclosed |
| WO-2007095631-A2 | NEW DRUG DELIVERY SYSTEM FOR CROSSING THE BLOOD BRAIN BARRIER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007095631-A2 | NEW DRUG DELIVERY SYSTEM FOR CROSSING THE BLOOD BRAIN BARRIER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | NDUFB7, NDUFB1, NDUFB3 | ALDH1A1 638/4885KDM4E 2305/4885TSHR 4717/4885 |
| US-20070203080-A1 | New Drug Delivery System for Crossing the Blood Brain Barrier | NDUFB5, NDUFB7, NDUFB3 | ALDH1A1 991/4885KDM4E 3016/4885TSHR 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.