SCHEMBL5146556

SCHEMBL5146556

CC(C)c1cc(Br)c(O)c(Br)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
GABRA1 P14867 4/20 0.48
GABRB2 P47870 2/20 0.48
GABRB1 P18505 3/20 0.46
ALOX12 P18054 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HIF1A Q16665 2/20 0.46
ALOX15 P16050 2/20 0.46
HPGD P15428 1/20 0.46
CASP1 P29466 1/20 0.46
RECQL P46063 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TTR P02766 2/20 0.41
MEN1 O00255 1/20 0.41
ALB P02768 1/20 0.41
KMT2A Q03164 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15998074 0.86 PTGS1 (0.43) CYP3A4TSHRTDP1GABRA1GABRB2
SCHEMBL6682827 0.86 GABRA1 (0.63) CYP3A4TSHRTDP1GABRA1GABRB2
SCHEMBL31075865 0.84 GABRA1 (0.45) CYP3A4TSHRTDP1GABRA1GABRB2
SCHEMBL21487683 0.84 ALDH1A1 (0.48) CYP3A4TSHRTDP1GABRA1GABRB2
SCHEMBL5911897 0.84 CYP3A4 (0.50) CYP3A4TSHRTDP1GABRA1GABRB2
SCHEMBL2986840 0.82 CYP3A4 (0.48) CYP3A4TSHRTDP1GABRA1GABRB2
SCHEMBL13219043 0.81 ALOX5 (0.60) ALOX12ALDH1A1ALOX15MEN1KMT2A
SCHEMBL26229436 0.80 ERN1 (0.58) GABRA1GABRB2GABRB1KDM4E
SCHEMBL4562076 0.78 ACHE (0.39) CYP3A4TSHRTDP1GABRA1GABRB2
SCHEMBL16860588 0.78 APEX1 (0.45) TDP1GABRA1GABRB2GABRB1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025230-A Method for recycling phenolic compounds from epoxy resin-based waste in high yield 四川大学 2025-05-23 CN claimed
US-4097547-A BARIUM CARBONATE, STRONTIUM CARBONATE AND/OR CALCIUM CARBONATE AS STABILIZERS MOBAY CHEMICAL CORPORATION (US) 1978-06-27 US claimed
CN-120025230-A Method for recycling phenolic compounds from epoxy resin-based waste in high yield 四川大学 2025-05-23 CN disclosed
CN-111454198-B Compound based on dipyridyl phenol/thiophenol and preparation method and application thereof 复旦大学 2023-02-10 CN disclosed
US-10813934-B2 Sirtuin modulators as inhibitors of cytomegalovirus THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2020-10-27 US disclosed
CN-111454198-A Compound based on dipyridyl phenol/thiophenol and preparation method and application thereof 复旦大学 2020-07-28 CN disclosed
US-20190192532-A1 COMBINATION THERAPY OF BROMODOMAIN INHIBITORS AND CHECKPOINT BLOCKADE PETER MACCALLUM CANCER INSTITUTE (AU) 2019-06-27 US disclosed
US-10308653-B2 Diazepane derivatives and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2019-06-04 US disclosed
US-20190000860-A1 USE OF COMPOSITIONS MODULATING CHROMATIN STRUCTURE FOR GRAFT VERSUS HOST DISEASE (GVHD) DANA-FARBER CANCER INSTITUTE, INC. (US) 2019-01-03 US disclosed
US-10042258-B2 Composition for forming a resist upper-layer film and method for producing a semiconductor device using the composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-08-07 US disclosed
US-20180169097-A1 COMBINATION THERAPY OF TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS DANA-FARBER CANCER INSTITUTE, INC. (US) 2018-06-21 US disclosed
US-20020013412-A1 Flame-retardant resin molding GENERAL ELECTRIC COMPANY 2002-01-31 US disclosed
WO-2001072905-A2 FLAME-RETARDANT RESIN MOLDING GENERAL ELECTRIC COMPANY (US) 2001-10-04 WO disclosed
WO-2001038438-A2 FLAME-RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE CONSISTING OF THE SAME GENERAL ELECTRIC COMPANY (US) 2001-05-31 WO disclosed
EP-0306838-A2 Process of preparing polycarbonates IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1989-03-15 EP disclosed
EP-0067857-B1 THERMOPLASTIC POLYCARBONATE RESINS REINFORCED WITH SILANE TREATED FILLERS GENERAL ELECTRIC COMPANY (US) 1986-02-19 EP disclosed
EP-0067857-A4 THERMOPLASTIC POLYCARBONATE RESINS REINFORCED WITH SILANE TREATED FILLERS. GEN ELECTRIC (US) 1983-05-16 EP disclosed
EP-0067857-A1 THERMOPLASTIC POLYCARBONATE RESINS REINFORCED WITH SILANE TREATED FILLERS. GEN ELECTRIC (US) 1982-12-29 EP disclosed
WO-1982002398-A1 THERMOPLASTIC POLYCARBONATE RESINS REINFORCED WITH SILANE TREATED FILLERS GEN ELECTRIC (US) 1982-07-22 WO disclosed
US-4131575-A Thermoplastic polycarbonate molding materials with improved mold release BAYER AKTIENGESELLSCHAFT (DE) 1978-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190000860-A1 USE OF COMPOSITIONS MODULATING CHROMATIN STRUCTURE FOR GRAFT VERSUS HOST DISEASE (GVHD) BCL6, BCL6B, EZH2 CYP3A4 4206/4885TSHR 4306/4885TDP1 2409/4885
US-10813934-B2 Sirtuin modulators as inhibitors of cytomegalovirus SIRT1, SIRT2, SIRT7 CYP3A4 4604/4885TSHR 4049/4885TDP1 1937/4885
US-10308653-B2 Diazepane derivatives and uses thereof BRDT, BRD4, BAZ2A CYP3A4 3930/4885TSHR 946/4885TDP1 1097/4885
US-20180169097-A1 COMBINATION THERAPY OF TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS CHUK, BCOR, MYC CYP3A4 4863/4885TSHR 2021/4885TDP1 662/4885
US-20190192532-A1 COMBINATION THERAPY OF BROMODOMAIN INHIBITORS AND CHECKPOINT BLOCKADE BRD4, BRD3, BRPF3 CYP3A4 4346/4885TSHR 2656/4885TDP1 683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.