Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817343 | 0.82 | USP2 (0.36) | CYP1A2CYP2C19TSHRALDH1A1LMNA | |
| SCHEMBL25013 | 0.81 | LMNA (0.41) | CYP2D6CYP1A2CYP2C19SLC6A3SLC6A2 | |
| SCHEMBL5148738 | 0.81 | USP2 (0.35) | CYP1A2CYP2C19TSHRALDH1A1LMNA | |
| SCHEMBL4756226 | 0.80 | USP2 (0.34) | CYP1A2CYP2C19TSHRALDH1A1LMNA | |
| SCHEMBL27641457 | 0.80 | ADRB2 (0.43) | CYP2D6CYP1A2SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4756846 | 0.79 | USP2 (0.33) | CYP1A2CYP2C19TSHRALDH1A1LMNA | |
| SCHEMBL1076766 | 0.78 | USP2 (0.39) | CYP1A2CYP2C19TSHRALDH1A1LMNA | |
| SCHEMBL4756232 | 0.78 | TP53 (0.38) | CYP2D6CYP1A2CYP2C19SLC6A3SLC6A2 | |
| SCHEMBL4756193 | 0.78 | LMNA (0.36) | CYP2D6CYP1A2CYP2C19SLC6A3SLC6A2 | |
| SCHEMBL6884986 | 0.77 | TP53 (0.37) | CYP2D6CYP1A2SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569895-A4 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1569895-A1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | Xenoport, Inc. (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052844-A1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2004-06-24 | — | — | WO | disclosed |