Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756193 | 0.87 | LMNA (0.36) | TP53TSHRCYP2D6KMT2ASLC6A2 | |
| SCHEMBL25013 | 0.84 | LMNA (0.41) | TP53TSHRCYP2D6KMT2ASLC6A2 | |
| SCHEMBL4756232 | 0.83 | TP53 (0.38) | TP53TSHRCYP2D6KMT2ASLC6A2 | |
| SCHEMBL27641457 | 0.80 | ADRB2 (0.43) | TSHRCYP2D6KMT2ASLC6A2SLC6A3 | |
| SCHEMBL5147376 | 0.77 | CYP2D6 (0.36) | TP53TSHRCYP2D6KMT2ASLC6A2 | |
| SCHEMBL27055 | 0.77 | CYP2D6 (0.40) | TP53TSHRCYP2D6KMT2ASLC6A2 | |
| SCHEMBL27622479 | 0.73 | CYP2D6 (0.40) | TSHRCYP2D6KMT2ASLC6A2SLC6A3 | |
| SCHEMBL27910096 | 0.73 | NPSR1 (0.43) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL1563323 | 0.73 | APOBEC3A (0.39) | TSHRKMT2ALMNAMEN1POLB | |
| SCHEMBL4700964 | 0.73 | LMNA (0.39) | TP53TSHRCYP2D6KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404324-A4 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT INC (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-1404324-A2 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | Xenoport, Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002100347-A2 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2002-12-19 | — | — | WO | disclosed |