Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1788206 | 0.78 | CES2 (0.52) | ALDH1A1NPC1HPGDMAPTCES2 | |
| Trifluoroacetic Acid SCHEMBL19123998 | 0.77 | CES1 (0.56) | ALDH1A1NPC1HPGDMAPTCES2 | |
| Trifluoroacetic Acid SCHEMBL2107014 | 0.73 | PLOD2 (0.46) | ALDH1A1MAPTCES2CES1MEN1 | |
| Trifluoroacetic Acid SCHEMBL27852892 | 0.73 | KMT2A (0.56) | ALDH1A1NPC1HPGDMAPTCES2 | |
| SCHEMBL22223648 | 0.73 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPTALOX15KMT2A | |
| SCHEMBL5147500 | 0.73 | ALDH1A1 (0.53) | ALDH1A1NPC1HPGDMAPTCES2 | |
| SCHEMBL5147755 | 0.72 | ALDH1A1 (0.45) | ALDH1A1NPC1HPGDMAPTCES2 | |
| SCHEMBL994062 | 0.71 | GAA (0.64) | ALDH1A1NPC1HPGDMAPTCES2 | |
| Hydrochloric Acid SCHEMBL30605742 | 0.70 | GAA (0.62) | ALDH1A1NPC1HPGDMAPTCES2 | |
| Water SCHEMBL30746017 | 0.70 | GAA (0.62) | ALDH1A1NPC1HPGDMAPTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112044-A1 | Thiadiazoline derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| EP-1671957-A1 | THIADIAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112044-A1 | Thiadiazoline derivative | TLK2, TLK1, BRWD1 | ALDH1A1 278/4885NPC1 3547/4885HPGD 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.