Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622028 | 0.88 | ALDH1A1 (0.53) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8399481 | 0.88 | GPR35 (0.58) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1374438 | 0.86 | GPR35 (0.48) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL14253715 | 0.86 | GPR35 (0.48) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL27957668 | 0.86 | GPR35 (0.48) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL25249470 | 0.86 | GPR35 (0.48) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3961070 | 0.86 | TSHR (0.58) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1372574 | 0.86 | GPR35 (0.48) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL17146169 | 0.86 | GPR35 (0.48) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL5681342 | 0.86 | ALDH1A1 (0.51) | GPR35TDP1TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849196-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |
| US-9631096-B2 | Dye compositions, methods of preparation, conjugates thereof, and methods of use | CORNELL UNIVERSITY (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2015-11-19 | — | — | US | disclosed |
| US-9181224-B2 | Bifunctional molecules with antibody-recruiting and entry inhibitory activity against the human immunodeficiency virus | YALE UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-8945515-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2015-02-03 | — | — | US | disclosed |
| US-20150011731-A1 | DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2015-01-08 | — | — | US | disclosed |
| WO-2013109859-A1 | DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2013-07-25 | — | — | WO | disclosed |
| US-20130035237-A1 | Nucleotides and Nucleosides and Methods for their Use in DNA Sequencing | AGILENT TECHNOLOGIES, INC. | 2013-02-07 | — | — | US | disclosed |
| EP-1865379-B1 | Method for resist pattern formation, and process for device prodution | CANON KK (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
| EP-0585980-A2 | Radiation sensitive materials and devices made therewith | AT&T Corp. (US) | 1994-03-09 | — | — | EP | disclosed |
| EP-0579420-A2 | Negative working resist material and pattern forming process | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0542485-A1 | Radiation curable compositions | Dow Corning Limited (GB) | 1993-05-19 | — | — | EP | disclosed |
| US-5200544-A | Acid generator, acid sensitive polymer; photosensitivity | AT&T BELL LABORATORIES (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0520642-A1 | Resist material and pattern formation process | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1992-12-30 | — | — | EP | disclosed |
| US-5135838-A | Resin sensitive to UV radiation and a nitrobenzyl compound that generates an acid | AT&T BELL LABORATORIES (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0440374-A2 | Chemical amplified resist material | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1991-08-07 | — | — | EP | disclosed |
| US-4996136-A | Radiation sensitive materials and devices made therewith | AT&T BELL LABORATORIES (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0330386-A2 | Radiation sensitive materials and devices made therewith | AT&T Corp. (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4430114-A | PREEMERGENCE, 5-//1-ETHYLPROPYL/AMINO/-4,6-DINITRO-O-TOLYLACETONITRILE | AMERICAN CYANAMID COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, PPOX, PRDX5 | GPR35 3634/4885TDP1 753/4885TSHR 4483/4885 |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, ARFGEF1, PRDX3 | GPR35 3541/4885TDP1 409/4885TSHR 4051/4885 |
| US-20130035237-A1 | Nucleotides and Nucleosides and Methods for their Use in DNA Sequencing | UNG, NT5C2, NT5E | GPR35 3104/4885TDP1 81/4885TSHR 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.