Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514833 | 0.88 | GPR35 (0.58) | GPR35TDP1ERN1ALDH1A1TSHR | |
| SCHEMBL11207636 | 0.86 | GPR35 (0.60) | GPR35TDP1ERN1ALDH1A1TSHR | |
| SCHEMBL7027335 | 0.85 | GPR35 (0.55) | GPR35TDP1ERN1ALDH1A1TSHR | |
| SCHEMBL9196646 | 0.83 | GPR35 (0.56) | GPR35TDP1ERN1ALDH1A1TSHR | |
| SCHEMBL4229187 | 0.83 | GPR35 (0.56) | GPR35TDP1ERN1ALDH1A1TSHR | |
| SCHEMBL13322828 | 0.83 | GPR35 (0.56) | GPR35TDP1ERN1TSHRCTSB | |
| SCHEMBL28120505 | 0.82 | GPR35 (0.51) | GPR35TDP1ERN1ALDH1A1TSHR | |
| SCHEMBL5622028 | 0.81 | ALDH1A1 (0.53) | GPR35TDP1ERN1ALDH1A1TSHR | |
| SCHEMBL13881142 | 0.80 | GPR35 (0.53) | GPR35TDP1ERN1TSHRCTSB | |
| SCHEMBL25249470 | 0.79 | GPR35 (0.48) | GPR35TDP1ERN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220180083-A1 | MODIFYING MESSAGES STORED IN MIXTURES OF MOLECULES USING THIN-LAYER CHROMATOGRAPHY | NORTHWESTERN UNIVERSITY | 2022-06-09 | — | — | US | disclosed |
| US-8748570-B2 | Insulin analogues | SYNGENE LIMITED (AU) | 2014-06-10 | — | — | US | disclosed |
| US-8748570-B2 | Insulin analogues | SYNGENE LIMITED (AU) | 2014-06-10 | — | — | US | disclosed |
| US-8748570-B2 | Insulin analogues | SYNGENE LIMITED (AU) | 2014-06-10 | — | — | US | disclosed |
| US-20130345397-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN PEPTIDES | SYNGENE LIMITED (AU) | 2013-12-26 | — | — | US | disclosed |
| EP-2576593-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN PEPTIDES | Syngene Limited (AU) | 2013-04-10 | — | — | EP | disclosed |
| EP-2576612-A1 | INSULIN ANALOGUES | Syngene Limited (AU) | 2013-04-10 | — | — | EP | disclosed |
| US-20120225811-A1 | INSULIN ANALOGUES | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 2012-09-06 | — | — | US | disclosed |
| US-20120225811-A1 | INSULIN ANALOGUES | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 2012-09-06 | — | — | US | disclosed |
| US-20120225811-A1 | INSULIN ANALOGUES | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 2012-09-06 | — | — | US | disclosed |
| WO-2011146973-A1 | INSULIN ANALOGUES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011146972-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN PEPTIDES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011146972-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN PEPTIDES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011146973-A1 | INSULIN ANALOGUES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |
| EP-0918757-A1 | 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS | GEORGETOWN UNIVERSITY (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997043268-A1 | 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS | GEORGETOWN UNIVERSITY (US) | 1997-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225811-A1 | INSULIN ANALOGUES | IAPP, INSR, GPR119 | GPR35 653/4885TDP1 4518/4885ERN1 3335/4885 |
| US-20130345397-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN PEPTIDES | DNPEP, NPPA, VIP | GPR35 4315/4885TDP1 3556/4885ERN1 2778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.