Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787547 | 0.88 | L3MBTL1 (0.50) | NPSR1TSHRALDH1A1MAPTKDM4E | |
| SCHEMBL14620656 | 0.86 | CES2 (0.48) | CES2NPSR1PRNPTSHRMAPK1 | |
| SCHEMBL788639 | 0.80 | NPSR1 (0.48) | NPSR1RXFP1MAPTKMT2ANPC1 | |
| SCHEMBL14409807 | 0.75 | CES2 (0.51) | CES2NPSR1PRNPTSHRMAPK1 | |
| SCHEMBL14620655 | 0.74 | L3MBTL1 (0.48) | NPSR1TSHRALDH1A1MAPTKDM4E | |
| SCHEMBL787663 | 0.74 | HSD11B1 (0.43) | NPSR1PRNPRXFP1ALDH1A1MAPT | |
| SCHEMBL30017661 | 0.73 | KDM4E (0.67) | CES2NPSR1PRNPTSHRMAPK1 | |
| SCHEMBL13338880 | 0.73 | KDM4E (0.67) | CES2NPSR1PRNPTSHRMAPK1 | |
| SCHEMBL10369463 | 0.73 | CA2 (0.52) | CES2NPSR1PRNPTSHRMAPK1 | |
| SCHEMBL806148 | 0.73 | L3MBTL1 (0.47) | NPSR1ALDH1A1MAPTKDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157454-B2 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI-AVENTIS (FR) | 2007-01-02 | — | — | US | disclosed |
| US-20040116353-A1 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI (FR) | 2004-06-17 | — | — | US | disclosed |