Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24924766 | 1.00 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL30867222 | 0.90 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL14483921 | 0.87 | CYP1A2 (0.61) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL29508434 | 0.87 | CYP1A2 (0.61) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL13560958 | 0.87 | CYP1A2 (0.61) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL28879791 | 0.87 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL7308713 | 0.86 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL29399499 | 0.86 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL28337005 | 0.85 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL22207790 | 0.85 | L3MBTL1 (0.49) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930476-A | Preparation method of (2S, 6R) -6-phenyl-2-piperidine carboxylate | 苏州弗莱明生物技术有限公司 | 2024-11-12 | — | — | CN | disclosed |
| US-20230257405-A1 | METHOD FOR PREPARING GLUFOSINATE OR ANALOGUES THEREOF | LIER CHEMICAL CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
| EP-4219512-A1 | METHOD FOR PREPARING GLUFOSINATE OR ANALOG THEREOF | Lier Chemical Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023001132-A1 | METHOD FOR PREPARING GLUFOSINATE OR ANALOG THEREOF | 利尔化学股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| US-7235687-B2 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfphonates) and compositions containing same | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2007-06-26 | — | — | US | disclosed |
| US-7235687-B2 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfphonates) and compositions containing same | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2007-06-26 | — | — | US | disclosed |
| US-20060135602-A1 | 4,4'-dithiobis(sodium 3-aminobutane-1-sulfonate)bis chlorohyrate or 4,4'-dithiobis(2,2 dimethylpropyl)-3-aminobutane-1-sulfonate)bis trifluoroacetate for example; treating arterial hypertension | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-06-22 | — | — | US | disclosed |
| WO-2004007441-A2 | NOVEL DERIVATIVES OF 4,4'-DITHIOBIS-(3-AMINOBUTANE-1-SULPHONATES) AND COMPOSITIONS CONTAINING SAME | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257405-A1 | METHOD FOR PREPARING GLUFOSINATE OR ANALOGUES THEREOF | FPGS, TYMP, GLUL | CYP1A2 2533/4885CYP2C9 2151/4885CYP2C19 2407/4885 |
| US-20060135602-A1 | 4,4'-dithiobis(sodium 3-aminobutane-1-sulfonate)bis chlorohyrate or 4,4'-dithiobis(2,2 dimethylpropyl)-3-aminobutane-1-sulfonate)bis trifluoroacetate for example; treating arterial hypertension | CBS, CTH, BHMT2 | CYP1A2 1677/4885CYP2C9 852/4885CYP2C19 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.