SCHEMBL5155437

SCHEMBL5155437

Cc1cc(C(O)(C=Cc2ccc(Cl)cc2)C(F)(F)F)ccc1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.40
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40
ESR1 P03372 2/20 0.38
AR P10275 1/20 0.38
ESR2 Q92731 1/20 0.38
AHR P35869 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
CYP3A4 P08684 1/20 0.33
LMNA P02545 2/20 0.32
HTT P42858 2/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5155426 1.00 PTGS1 (0.40) PTGS1ALOX5PTGS2ESR1AR
SCHEMBL5155430 1.00 PTGS1 (0.40) PTGS1ALOX5PTGS2ESR1AR
SCHEMBL5149151 0.77 ESR1 (0.45) ESR1ARESR2SMN1; SMN2MEN1
SCHEMBL13734748 0.76 CYP1B1 (0.41) AHRSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL13734744 0.76 CYP1B1 (0.41) AHRSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL5155513 0.75 SMN1; SMN2 (0.39) SMN1; SMN2MEN1KMT2ACYP3A4LMNA
SCHEMBL5155508 0.75 SMN1; SMN2 (0.39) SMN1; SMN2MEN1KMT2ACYP3A4LMNA
SCHEMBL5154470 0.72 ESR1 (0.40) ESR1ARESR2SMN1; SMN2MEN1
SCHEMBL5154597 0.71 CCR6 (0.41) ESR1ARESR2SMN1; SMN2MEN1
SCHEMBL5151363 0.70 ESR1 (0.40) ESR1ARESR2SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-02-22 US disclosed
EP-1671941-A1 SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2006-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent L3MBTL1, L3MBTL3, L3MBTL4 PTGS1 1992/4885ALOX5 446/4885PTGS2 2977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.