Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.42 |
| ▸ | CASP1 | P29466 | 5/20 | 0.42 |
| ▸ | CASP7 | P55210 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL10475846 | 0.90 | HRH4 (0.47) | HRH4KDM4EALDH1A1ALOX15CASP1 | |
| SCHEMBL15831807 | 0.85 | HRH4 (0.56) | HRH4KDM4EALDH1A1ALOX15CASP1 | |
| SCHEMBL15831793 | 0.84 | HRH4 (0.61) | HRH4KDM4EALDH1A1ALOX15CASP1 | |
| SCHEMBL6949334 | 0.84 | HRH4 (0.55) | HRH4KDM4EALDH1A1ALOX15CASP1 | |
| SCHEMBL14781363 | 0.83 | HRH4 (0.60) | HRH4KDM4EALDH1A1ALOX15CASP1 | |
| SCHEMBL2553146 | 0.83 | HRH4 (0.60) | HRH4KDM4EALDH1A1ALOX15CASP1 | |
| SCHEMBL7066926 | 0.83 | HRH4 (0.60) | HRH4KDM4EALDH1A1ALOX15CASP1 | |
| SCHEMBL2527319 | 0.80 | HRH4 (0.61) | HRH4KDM4EALDH1A1ALOX15CASP1 | |
| SCHEMBL6821415 | 0.80 | ALDH1A1 (0.58) | HRH4KDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL1735639 | 0.80 | HRH4 (0.57) | HRH4KDM4EALDH1A1ALOX15CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | GRUENENTHAL GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | TRPV1, TRPV5, TRPV2 | HRH4 45/4885KDM4E 4191/4885ALDH1A1 2444/4885 |
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | OPRM1, GRM5, OPRD1 | HRH4 55/4885KDM4E 3490/4885ALDH1A1 2610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.