Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51601 | 0.87 | TDP1 (0.68) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL28875175 | 0.87 | TDP1 (0.68) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL21953404 | 0.83 | TDP1 (0.67) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL514994 | 0.82 | TDP1 (0.68) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| Ethylene Glycol SCHEMBL15661698 | 0.81 | ALDH1A1 (0.62) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL514606 | 0.80 | TPMT (0.43) | TDP1SLC6A2KMT2ALMNAALDH1A1 | |
| SCHEMBL514789 | 0.80 | TDP1 (0.55) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL513611 | 0.80 | TDP1 (0.53) | TDP1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL514973 | 0.80 | LMNA (0.61) | SLC6A3KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL514540 | 0.79 | LMNA (0.60) | TDP1MAPK1HIF1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| US-11149052-B2 | 2′3′-cyclic dinucleotides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2021-10-19 | — | — | US | disclosed |
| EP-3774832-A1 | 3'3'-CYCLIC DINUCLEOTIDES | Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. (CZ) | 2021-02-17 | — | — | EP | disclosed |
| EP-3774831-A1 | 2'3'-CYCLIC DINUCLEOTIDES | Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. (CZ) | 2021-02-17 | — | — | EP | disclosed |
| US-20190322697-A1 | 2'2'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR,V.V.I. (CZ) | 2019-10-24 | — | — | US | disclosed |
| US-20190322695-A1 | 2'3'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR,V.V.I. (CZ) | 2019-10-24 | — | — | US | disclosed |
| US-20190322696-A1 | 3'3'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR,V.V.I. (CZ) | 2019-10-24 | — | — | US | disclosed |
| WO-2019193543-A1 | 3'3'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2019-10-10 | — | — | WO | disclosed |
| WO-2019193533-A1 | 2'2'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2019-10-10 | — | — | WO | disclosed |
| WO-2019193542-A1 | 2'3'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2019-10-10 | — | — | WO | disclosed |
| WO-2014184070-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014184071-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| EP-2420493-A1 | HALOALKYLSULFONANILIDE DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20120029187-A1 | HALOALKYLSULFONANILIDE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2336104-A1 | ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE | Nissan Chemical Industries, Ltd. (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-5837871-A | PHOSPHONATE DERIVATIVES; ANTITUMOR AGENTS, VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-11-17 | — | — | US | disclosed |
| US-5693798-A | ACTIVE AGAINST RETROVIRAL DISEASES; PROPHYLAXIS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322697-A1 | 2'2'-CYCLIC DINUCLEOTIDES | STING1, CGAS, MAVS | TDP1 173/4885MAPK1 2686/4885HIF1A 3163/4885 |
| US-11149052-B2 | 2′3′-cyclic dinucleotides | STING1, MAVS, CGAS | TDP1 216/4885MAPK1 2779/4885HIF1A 3021/4885 |
| US-20190322695-A1 | 2'3'-CYCLIC DINUCLEOTIDES | STING1, MAVS, CGAS | TDP1 170/4885MAPK1 2827/4885HIF1A 3158/4885 |
| US-20120029187-A1 | HALOALKYLSULFONANILIDE DERIVATIVE | CBR3, CBR1, HDHD5 | TDP1 3903/4885MAPK1 1508/4885HIF1A 3920/4885 |
| US-20190322696-A1 | 3'3'-CYCLIC DINUCLEOTIDES | STING1, CGAS, MAVS | TDP1 201/4885MAPK1 2722/4885HIF1A 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.