Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156279 | 0.88 | CA1 (0.42) | RORCALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL5155038 | 0.88 | CA1 (0.42) | RORCALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL4762136 | 0.87 | MCL1 (0.49) | RORCALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL5151586 | 0.86 | CA1 (0.40) | RORCALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5151357 | 0.84 | KDM4E (0.51) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL5152597 | 0.78 | FBP1 (0.45) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL5152108 | 0.77 | CA1 (0.43) | RORCALDH1A1KDM4EHTTCA1 | |
| SCHEMBL5156271 | 0.77 | CA1 (0.43) | RORCALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5151594 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL4762138 | 0.76 | MCL1 (0.45) | RORCALDH1A1HTTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225284-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | claimed |
| US-20070225284-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225284-A1 | Inhibitors of soluble adenylate cyclase | ADCY1, ADCY2, ADCYAP1R1 | RORC 3354/4885ALDH1A1 235/4885KDM4E 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.