SCHEMBL5150171

SCHEMBL5150171

Cc1c(O)ccc(Sc2ccc(O)c(C)c2C)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.50
HSD17B10 Q99714 4/20 0.50
TP53 P04637 4/20 0.50
MEN1 O00255 3/20 0.50
HPGD P15428 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 3/20 0.50
GAA P10253 3/20 0.50
LMNA P02545 2/20 0.50
ALOX12 P18054 2/20 0.50
ALDH1A1 P00352 5/20 0.39
HTT P42858 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP3A4 P08684 2/20 0.39
HIF1A Q16665 2/20 0.39
PLA2G1B P04054 1/20 0.39
HSP90AA1 P07900 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29599714 1.00 ALOX15 (0.50) ALOX15HSD17B10TP53MEN1HPGD
SCHEMBL5570280 0.84 GAA (0.39) ALOX15HSD17B10TP53MEN1HPGD
SCHEMBL8373565 0.83 SIRT1 (0.43) MEN1HPGDKMT2AMAPTGAA
SCHEMBL1507626 0.82 ALOX15 (0.43) ALOX15HSD17B10TP53MEN1HPGD
SCHEMBL10807095 0.82 ALOX15 (0.48) ALOX15HSD17B10TP53MEN1HPGD
SCHEMBL8374173 0.81 ALOX15 (0.44) ALOX15HSD17B10TP53MEN1HPGD
SCHEMBL68013 0.80 TRPA1 (0.53) ALOX15HSD17B10TP53MEN1HPGD
SCHEMBL29457565 0.80 TRPA1 (0.53) ALOX15HSD17B10TP53MEN1HPGD
SCHEMBL12339855 0.78 ALOX15 (0.45) ALOX15HSD17B10TP53MEN1HPGD
SCHEMBL2807223 0.77 TRPA1 (0.54) ALOX15HSD17B10TP53MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640590-A1 Process for the synthesis of 4-mercaptophenols and naphthalenols Bristol-Myers Company (US) 1995-03-01 EP claimed
EP-0482342-A2 Hypocholesterolemic unsymmetrical dithiol ketals Bristol-Myers Squibb Company (US) 1992-04-29 EP claimed
US-4518977-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-05-21 US claimed
US-11524514-B2 Tamper-proof medium for thermal printing OMYA INTERNATIONAL AG (CH) 2022-12-13 US disclosed
CN-110799345-B Tamper-resistant media for thermal printing 欧米亚国际集团 2022-04-19 CN disclosed
EP-3642044-B1 TAMPER-PROOF MEDIUM FOR THERMAL PRINTING OMYA INT AG (CH) 2021-07-28 EP disclosed
US-20200198386-A1 TAMPER-PROOF MEDIUM FOR THERMAL PRINTING OMYA INTERNATIONAL AG (CH) 2020-06-25 US disclosed
EP-3642044-A1 TAMPER-PROOF MEDIUM FOR THERMAL PRINTING Omya International AG (CH) 2020-04-29 EP disclosed
EP-3418064-A1 TAMPER-PROOF MEDIUM FOR THERMAL PRINTING Omya International AG (CH) 2018-12-26 EP disclosed
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US disclosed
EP-1448397-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO THERMAL OY (FI) 2007-07-11 EP disclosed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US disclosed
US-4628336-A POLYPHENYL ESTERS; SOIL RESISTANCE; IMAGE STABILITY JUJO PAPER CO., LTD. (JP) 1986-12-09 US disclosed
EP-0189760-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-08-06 EP disclosed
US-4590499-A MONOBENZYL CALCIUM PHTHALATE OR ZINC P-NITROBENZOATE AS STABILIZER IN THE CHROMOGEN LAYER; OIL REPELLENTS JUJO PAPER CO., LTD. (JP) 1986-05-20 US disclosed
US-4573062-A HYDROXYBENZ/YLOXYBENZOIC ACID COLOR DEVELOPER AND LEUCO DYE JUJO PAPER CO., LTD. (JP) 1986-02-25 US disclosed
EP-0171810-A2 Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-02-19 EP disclosed
EP-0168819-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-01-22 EP disclosed
EP-0154336-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-09-11 EP disclosed
US-4518977-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-05-21 US disclosed