SCHEMBL5570280

SCHEMBL5570280

Cc1c(O)ccc(SSc2ccc(O)c(C)c2C)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.39
ALOX15 P16050 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TP53 P04637 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
TRPA1 O75762 2/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.33
MAPK1 P28482 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.32
ACHE P22303 1/20 0.32
AR P10275 2/20 0.32
ESR1 P03372 6/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29599714 0.84 ALOX15 (0.50) GAAALOX15HSD17B10TP53MEN1
SCHEMBL5150171 0.84 ALOX15 (0.50) GAAALOX15HSD17B10TP53MEN1
SCHEMBL1507626 0.82 ALOX15 (0.43) GAAALOX15HSD17B10TP53MEN1
SCHEMBL29457565 0.80 TRPA1 (0.53) GAAALOX15HSD17B10TP53MEN1
SCHEMBL68013 0.80 TRPA1 (0.53) GAAALOX15HSD17B10TP53MEN1
SCHEMBL3719399 0.77 GAA (0.34) GAAALOX15HSD17B10TP53MEN1
SCHEMBL9367675 0.75 TRPA1 (0.37) GAAALOX15HSD17B10TP53MEN1
SCHEMBL4606273 0.75 AR (0.38) GAAALOX15HSD17B10TP53MEN1
SCHEMBL8342074 0.75 ALDH1A1 (0.35) GAAALOX15HSD17B10TP53MEN1
SCHEMBL8373565 0.73 SIRT1 (0.43) GAAMEN1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1749037-A1 PERFLUORINATED ESTERS, POLYESTER, ETHERS AND CARBONATES Ciba SC Holding AG (CH) 2007-02-07 EP disclosed
WO-2005116099-A1 PERFLUORINATED ESTERS, POLYESTER, ETHERS AND CARBONATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-12-08 WO disclosed
EP-0768573-B1 Phosphor-containing photosensitive resin composition for use in manufacturing plasma display panel HITACHI CHEMICAL CO LTD (JP) 2003-07-30 EP disclosed
EP-0711813-B1 Antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 2001-07-25 EP disclosed
US-6248501-B1 RESINS WITH CARBOXY GROUPS AND ETHYLENEIC UNSATURATED COMPOUNDS HITACHI CHEMICAL CO., LTD. (JP) 2001-06-19 US disclosed
US-6077647-A BACK PLATE FOR PLASMA DISPLAY PANEL HITACHI CHEMICAL CO., LTD. (JP) 2000-06-20 US disclosed
US-5858616-A Photosensitive resin composition, photosensitive film and process for preparing fluorescent pattern using the same, and phosphor subjected to surface treatment and process for preparing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1999-01-12 US disclosed
US-5773508-A BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-06-30 US disclosed
EP-0608131-B1 Resin composition and antifouling paint HITACHI CHEMICAL CO LTD (JP) 1998-06-17 EP disclosed
EP-0608132-B1 Coating varnish composition and antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 1998-05-20 EP disclosed
EP-0768573-A1 Phosphor-containing photosensitive resin composition for use in manufacturing plasma display panel Hitachi Chemical Co., Ltd. (JP) 1997-04-16 EP disclosed
US-5550202-A STORAGE STABILITY; LONG LASTING HITACHI CHEMICAL CO., LTD. (JP) 1996-08-27 US disclosed
EP-0711813-A2 Coating varnish composition and antifouling coating composition Hitachi Chemical Co., Ltd. (JP) 1996-05-15 EP disclosed
US-5439511-A Composition containing polymer obtained by polymerizing unsaturated acid anhydride and another unsaturated compound, specified additive HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-08-08 US disclosed
US-5439512-A Contains a triazole, thiadiazole or benzotriazole derivative HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-08-08 US disclosed
EP-0659848-A2 Coating composition and antifouling paint Hitachi Chemical Co., Ltd. (JP) 1995-06-28 EP disclosed
US-5356979-A Addition polymers for underwater structures HITACHI CHEMICAL COMPANY, LTD. (JP) 1994-10-18 US disclosed
EP-0608131-A1 Resin composition and antifouling paint HITACHI CHEMICAL CO., LTD. (JP) 1994-07-27 EP disclosed
EP-0608132-A1 Coating varnish composition and antifouling coating composition HITACHI CHEMICAL CO., LTD. (JP) 1994-07-27 EP disclosed
EP-0550998-A1 Coating resin and antifouling coating composition HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-07-14 EP disclosed