SCHEMBL5151141

SCHEMBL5151141

Nc1scc(-c2ccccc2)c1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
LMNA P02545 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
HPGD P15428 1/20 0.51
PRKCZ Q05513 1/20 0.51
TDO2 P48775 2/20 0.47
HSD17B10 Q99714 2/20 0.46
DAPK3 O43293 1/20 0.46
PRKD3 O94806 1/20 0.46
MAP4K4 O95819 1/20 0.46
ABL1 P00519 1/20 0.46
NTRK1 P04629 1/20 0.46
LCK P06239 1/20 0.46
CSF1R P07333 1/20 0.46
RET P07949 1/20 0.46
MET P08581 1/20 0.46
PDGFRB P09619 1/20 0.46
FGFR1 P11362 1/20 0.46
PDGFRA P16234 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8219401 0.82 ALDH1A1 (0.49) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL28229021 0.80 ALDH1A1 (0.47) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL29217099 0.77 DAPK3 (0.43) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL28801323 0.77 MAP4K4 (0.43) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL29217102 0.77 DAPK3 (0.43) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL27653910 0.76 PBRM1 (0.51) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL17636789 0.76 ALDH1A1 (0.47) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL1799330 0.76 KMT2A (0.69) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL9422075 0.76 PRKCZ (0.55) ALDH1A1LMNAMEN1KMT2AHPGD
SCHEMBL3799837 0.76 ALDH1A1 (0.47) ALDH1A1LMNAMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US claimed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US claimed
CN-104927053-B Polyimide precursor composition, the method for preparing polyimides formed body and polyimides formed body 富士施乐株式会社 2018-07-13 CN disclosed
CN-105315665-A Polyimide precursor composition, method for preparing polyimide precursor, polyimide molded article, and method for preparing polyimide molded article FUJI XEROX CO LTD 2016-02-10 CN disclosed
CN-105295374-A Polyimide precursor composition, method for preparing polyimide precursor, polyimide molded article, and method for preparing polyimide molded article FUJI XEROX CO LTD 2016-02-03 CN disclosed
CN-104927053-A POLYIMIDE PRECURSOR COMPOSITION, METHOD FOR MANUFACTURING POLYIMIDE MOLDED BODY, AND POLYIMIDE MOLDED BODY FUJI XEROX CO LTD 2015-09-23 CN disclosed
CN-104710788-A POLYIMIDE PRECURSOR COMPOSITION, METHOD OF PRODUCING POLYIMIDE PRECURSOR COMPOSITION, METHOD OF PRODUCING POLYIMIDE MOLDED ARTICLE, POLYIMIDE MOLDED ARTICLE, LIQUID CRYSTAL ALIGNMENT FILM, PASSIVATION FILM, WIRE COATING MATERIAL, AND ADHESIVE FILM FUJI XEROX CO LTD 2015-06-17 CN disclosed
CN-102079876-B Organic semiconductor orientation composition, organic semiconductor orientation film, organic semiconductor element and method for manufacturing same JSR CO., LTD. (JP) 2014-10-15 CN disclosed
CN-103965625-A Polyimide precursor composition and method for producing polyimide precursor composition FUJI XEROX CO LTD 2014-08-06 CN disclosed
CN-103965473-A POLYIMIDE PRECURSOR COMPOSITION AND METHOD FOR PREPARING POLYIMIDE PRECURSOR COMPOSITION FUJI XEROX CO LTD 2014-08-06 CN disclosed
CN-102041007-B Liquid crystal aligning agent, liquid crystal display element and polyorganosiloxane compound JSR CORP 2014-03-19 CN disclosed
EP-1737417-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2007-01-03 EP disclosed
CN-1263825-C Liquid crystal orientation agent, formation method of liquid crystal orientation membrane and liquid crystal display unit JSR CORP (JP) 2006-07-12 CN disclosed
CN-1721502-A Liquid crystal aligning agent and liquid crystal display element JSR CORP (JP) 2006-01-18 CN disclosed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US disclosed
WO-2005074875-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-08-18 WO disclosed
CN-1196768-C Liquid crystal aligning agent and liquid crystal display device JAPAN SYNTHETIC RUBBER CO LTD (JP) 2005-04-13 CN disclosed
CN-1442466-A Liquid crystal orientation agent, formation method of liquid crystal orientation membrane and liquid crystal display unit JSR CORP (JP) 2003-09-17 CN disclosed
CN-1408817-A Liquid crystal aligning agent and liquid crystal display element JSR CORP (JP) 2003-04-09 CN disclosed
CN-1140195-A Liquid crystal aligning agent and liquid crystal display device JAPAN SYNTHETIC RUBBER CO LTD (JP) 1997-01-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, CKMT1A; CKMT1B, CYB5R3 ALDH1A1 782/4885LMNA 1256/4885MEN1 4871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.