Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154021 | 0.89 | THRB (0.33) | ALDH1A1THRBPAX8 | |
| SCHEMBL14573947 | 0.83 | THRB (0.33) | ALDH1A1THRBPAX8 | |
| SCHEMBL14607671 | 0.82 | HRH2 (0.39) | ALDH1A1THRB | |
| SCHEMBL14607694 | 0.81 | HRH2 (0.41) | — | |
| SCHEMBL14573940 | 0.81 | HRH2 (0.33) | ALDH1A1THRBPAX8 | |
| SCHEMBL5150806 | 0.72 | MEN1 (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5155296 | 0.71 | MEN1 (0.33) | ALDH1A1 | |
| SCHEMBL2015730 | 0.67 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL9795442 | 0.67 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL2010219 | 0.66 | ALDH1A1 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037821-A1 | Nitrosated glutamic acid compounds, compositions and methods of use | NITROMED, INC. (US) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037821-A1 | Nitrosated glutamic acid compounds, compositions and methods of use | GLS, NOS2, NOS1 | ALDH1A1 883/4885THRB 1611/4885PAX8 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.