Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 5/20 | 0.52 |
| ▸ | MET | P08581 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | PARG | Q86W56 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150145 | 0.84 | PGR (0.50) | PNLIPPARGBRAF | |
| SCHEMBL2260442 | 0.83 | MET (0.55) | PNLIPMETEPHX2KCNQ3KCNQ2 | |
| SCHEMBL14949681 | 0.83 | CDK8 (0.55) | MET | |
| SCHEMBL4688816 | 0.82 | STK39 (0.51) | PNLIPPARGBRAFKDRRAF1 | |
| SCHEMBL4687674 | 0.82 | RAB9A (0.51) | PNLIP | |
| SCHEMBL4738957 | 0.81 | HSPB1 (0.63) | PNLIPMETFFAR1KDR | |
| SCHEMBL4738967 | 0.81 | HSPB1 (0.63) | PNLIPMETFFAR1KDR | |
| SCHEMBL1137330 | 0.80 | MET (0.73) | METBRAFKDR | |
| SCHEMBL4314966 | 0.80 | MEN1 (0.53) | METRAF1 | |
| SCHEMBL4683815 | 0.80 | SLC1A3 (0.46) | PNLIPMETKCNQ3KCNQ2KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |