Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13469120 | 0.87 | L3MBTL1 (0.70) | KMT2AL3MBTL1ALDH1A1POLBTAS1R3 | |
| SCHEMBL5553160 | 0.83 | POLB (0.55) | KMT2AL3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL14643391 | 0.83 | KDM4E (0.63) | KMT2AL3MBTL1KDM4EALDH1A1HTT | |
| SCHEMBL10584522 | 0.83 | L3MBTL1 (0.58) | KMT2AL3MBTL1ALDH1A1POLBTAS1R3 | |
| SCHEMBL10027975 | 0.83 | KDM4E (0.63) | KMT2AL3MBTL1KDM4EALDH1A1HTT | |
| SCHEMBL12125170 | 0.83 | KDM4E (0.63) | KMT2AL3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL13018960 | 0.81 | KDM4E (0.61) | KMT2AL3MBTL1KDM4EALDH1A1HTT | |
| SCHEMBL9860802 | 0.81 | TAS1R3 (0.55) | KMT2AL3MBTL1ALDH1A1POLBTAS1R3 | |
| SCHEMBL13255717 | 0.81 | L3MBTL1 (0.58) | KMT2AL3MBTL1ALDH1A1POLBTAS1R3 | |
| SCHEMBL13018961 | 0.81 | KCNQ2 (0.66) | KMT2AL3MBTL1KDM4EALDH1A1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558617-A4 | AMIDINE COMPOUNDS | UNIV MONASH (AU) | 2007-07-11 | — | — | EP | disclosed |
| US-20060111381-A1 | Amidine compounds | MONASH UNIVERSITY (AU) | 2006-05-25 | — | — | US | disclosed |
| EP-1558617-A1 | AMIDINE COMPOUNDS | Monash University (AU) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004033458-A1 | AMIDINE COMPOUNDS | MONASH UNIVERSITY (AU) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111381-A1 | Amidine compounds | OPRM1, OPRD1, OPRK1 | KMT2A 2882/4885L3MBTL1 2079/4885KDM4E 2690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.