Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | ICMT | O60725 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154476 | 0.84 | CCNT1 (0.48) | KMT2AMEN1USP2TSHRCNR2 | |
| SCHEMBL28665118 | 0.73 | CDC25A (0.58) | KMT2AMEN1POLBCNR2ICMT | |
| SCHEMBL4601912 | 0.73 | SCN9A (0.50) | KMT2AMEN1POLBUSP2TSHR | |
| SCHEMBL19068192 | 0.71 | POLB (0.46) | KMT2AMEN1POLBUSP2TSHR | |
| SCHEMBL17176648 | 0.69 | RAB9A (0.64) | KMT2AMEN1POLBCNR2HTR3A | |
| SCHEMBL27597588 | 0.69 | POLB (0.45) | KMT2AMEN1POLBTSHRCNR2 | |
| SCHEMBL17170689 | 0.69 | TSHR (0.67) | KMT2AMEN1POLBTSHRCNR2 | |
| SCHEMBL21600839 | 0.68 | MEN1 (0.47) | KMT2AMEN1POLBTSHRCNR2 | |
| SCHEMBL30808127 | 0.68 | HTR6 (0.39) | KMT2AHTR6ICMT | |
| SCHEMBL15459561 | 0.67 | CYP19A1 (0.51) | KMT2AMEN1USP2ICMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | KMT2A 916/4885MEN1 410/4885POLB 4403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.