Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265454 | 0.85 | TSHR (0.33) | ESR1ESR2 | |
| SCHEMBL8018745 | 0.81 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL4630071 | 0.78 | — | — | |
| SCHEMBL2198447 | 0.75 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL1224337 | 0.75 | CA4 (0.38) | ESR1ESR2 | |
| SCHEMBL8040586 | 0.74 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL10606245 | 0.72 | ORAI1 (0.32) | ESR1ESR2 | |
| SCHEMBL21923149 | 0.71 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL19755901 | 0.71 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL7787435 | 0.71 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328529-B1 | WELL-DEFINED NANOSIZED BUILDING BLOCKS FOR ORGANIC/INORGANIC NANOCOMPOSITES | UNIV MICHIGAN (US) | 2007-01-10 | — | — | EP | disclosed |
| US-20060083925-A1 | Well-defined nanosized building blocks for organic/inorganic nanocomposites | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2006-04-20 | — | — | US | disclosed |
| US-6927301-B2 | Well-defined nanosized building blocks for organic/inorganic nanocomposites | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-08-09 | — | — | US | disclosed |
| EP-1328529-A1 | WELL-DEFINED NANOSIZED BUILDING BLOCKS FOR ORGANIC/INORGANIC NANOCOMPOSITES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20030120099-A1 | Well-defined nanosized building blocks for organic/inorganic nanocomposites | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2003-06-26 | — | — | US | disclosed |
| WO-2002100867-A1 | WELL-DEFINED NANOSIZED BUILDING BLOCKS FOR ORGANIC/INORGANIC NANOCOMPOSITES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2002-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120099-A1 | Well-defined nanosized building blocks for organic/inorganic nanocomposites | NOXO1, FES, QSOX1 | ESR1 2423/4885ESR2 1246/4885NR1H2 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.