Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18038413 | 0.72 | — | — | |
| SCHEMBL4422422 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL28264588 | 0.69 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7579549 | 0.68 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL4417975 | 0.68 | — | — | |
| SCHEMBL9951425 | 0.68 | ALDH1A1 (0.42) | ALDH1A1GSR | |
| Nitric Acid SCHEMBL10435391 | 0.67 | CA5A (0.35) | ALDH1A1GSR | |
| SCHEMBL20485989 | 0.67 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8277389 | 0.66 | — | — | |
| SCHEMBL10577977 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282519-B2 | Nitrosated and nitrosylated diuretic compounds, compositions and methods of use | NITROMED, INC. (US) | 2007-10-16 | — | — | US | disclosed |
| US-20050059655-A1 | Nitrosated and nitrosylated diuretic compounds, compositions and methods of use | NITROMED, INC. (US) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059655-A1 | Nitrosated and nitrosylated diuretic compounds, compositions and methods of use | REN, NOS1, NOS3 | ALDH1A1 396/4885GSR 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.