Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601336 | 0.91 | CCKBR (0.39) | CCKBRNOTUMMTNR1AMTNR1BHTR2A | |
| SCHEMBL4602247 | 0.83 | HDAC3 (0.41) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL14557647 | 0.83 | HDAC3 (0.41) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL14557719 | 0.80 | ITGB2 (0.39) | CCKBRNOTUMMTNR1AMTNR1BHTR2A | |
| SCHEMBL14610637 | 0.80 | ICMT (0.41) | CCKBRNOTUMMTNR1AMTNR1BHTR2A | |
| SCHEMBL14557731 | 0.79 | NR3C1 (0.40) | CCKBRNOTUMMTNR1AMTNR1BHTR2A | |
| SCHEMBL14557691 | 0.79 | HTR2A (0.40) | CCKBRNOTUMMTNR1AMTNR1BHTR2A | |
| SCHEMBL4600979 | 0.79 | TDO2 (0.42) | CCKBRNOTUMMTNR1AMTNR1BHTR2A | |
| SCHEMBL14557728 | 0.79 | HTR2A (0.38) | CCKBRNOTUMMTNR1AMTNR1BHTR2A | |
| SCHEMBL4603009 | 0.79 | ROCK2 (0.43) | CCKBRHTR2AHTR1ASPRHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | CCKBR 249/4885NOTUM 2978/4885MTNR1A 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.