SCHEMBL51567

SCHEMBL51567

N#Cc1ccc(O)c(Cc2cc(C#N)ccc2O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.48
HSPA5 P11021 2/20 0.48
MEN1 O00255 1/20 0.48
SLC22A1 O15245 1/20 0.48
USP2 O75604 1/20 0.48
LMNA P02545 1/20 0.48
HSP90AA1 P07900 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
HSPD1 P10809 1/20 0.48
IDO1 P14902 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HTT P42858 1/20 0.48
BLM P54132 1/20 0.48
HSPE1 P61604 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11339561 0.86 HIF1A (0.45) HIF1AHSPA5MEN1SLC22A1USP2
SCHEMBL6214320 0.85 KLF10 (0.46) MEN1KMT2ACA12CA2CA3
SCHEMBL25054203 0.83 LOXL2 (0.47) CA12CA2CA3CA6CA9
SCHEMBL12594178 0.83 AR (0.54) HSP90AA1CA12CA2CA3CA6
SCHEMBL50978 0.83 CA12 (0.44) HSPA5MEN1MAPTKMT2ACA12
SCHEMBL1400680 0.80 ALOX5 (0.46) MEN1KMT2ACA12CA2CA3
SCHEMBL8388814 0.80 KDM4E (0.55) MEN1MAPTALOX15HTTKMT2A
SCHEMBL4771536 0.79 GABRA1 (0.58) HIF1AMEN1USP2LMNAHSP90AA1
SCHEMBL1400243 0.79 GABRA1 (0.59) MEN1LMNACYP3A4MAPTHPGD
SCHEMBL12207176 0.78 AMY1A (0.48) HIF1AHSPA5MEN1SLC22A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8129307-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-03-06 US disclosed
US-20110269622-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-11-03 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
EP-2112001-B1 THERMOSENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2011-05-11 EP disclosed
EP-2261045-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2010-12-15 EP disclosed
EP-2181853-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2010-05-05 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
US-7141359-B2 Developers for thermal recording materials and thermal recording materials API CORPORATION (JP) 2006-11-28 US disclosed
US-20050118526-A1 Developers for thermal recording materials and thermal recording materials MITSUBISHI CHEMICAL CORPORATION (JP) 2005-06-02 US disclosed
EP-1393923-A1 DEVELOPERS FOR THERMAL RECORDING MATERIALS AND THERMAL RECORDING MATERIALS API Corporation (JP) 2004-03-03 EP disclosed