Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511191 | 0.83 | CASP3 (0.81) | CASP3TTRCES1NR1H3APP | |
| SCHEMBL28263 | 0.83 | CASP3 (0.81) | CASP3TTRCES1NR1H3APP | |
| SCHEMBL14887957 | 0.83 | CASP3 (0.41) | CASP3TTRCES1POLBCA2 | |
| Hydrogen Sulfide SCHEMBL11121709 | 0.80 | CASP3 (0.77) | CASP3TTRCES1APPMEN1 | |
| Hydrogen Sulfide SCHEMBL11098631 | 0.80 | CASP3 (0.77) | CASP3TTRCES1APPMEN1 | |
| SCHEMBL29025703 | 0.80 | CASP3 (0.77) | CASP3TTRCES1NR1H3APP | |
| Water SCHEMBL9398503 | 0.80 | CASP3 (0.77) | CASP3TTRCES1NR1H3APP | |
| Hydrochloric Acid SCHEMBL7736926 | 0.80 | CASP3 (0.77) | CASP3TTRCES1NR1H3APP | |
| Iodide SCHEMBL30725965 | 0.80 | CASP3 (0.77) | CASP3TTRCES1NR1H3APP | |
| SCHEMBL19450565 | 0.78 | ERCC1 (0.53) | CES1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6451067-B1 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-09-17 | — | — | US | claimed |
| EP-0847749-B1 | Use of diiminoisoindoline or 3-aminoisoindolone derivatives for the dyeing of keratinic fibers and compositions containing them | OREAL (FR) | 1999-12-01 | — | — | EP | claimed |
| EP-0847749-A1 | Use of diiminoisoindoline or 3-aminoisoindolone derivatives for the dyeing of keratinic fibers and compositions containing them | L'OREAL (FR) | 1998-06-17 | — | — | EP | claimed |
| EP-3227376-B1 | HIGH MELT FLOW POLYETHERIMIDE-SILOXANE COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES MADE THEREFROM | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-03-13 | — | — | EP | disclosed |
| US-20130102627-A1 | Acridines As Inhibitors Of Haspin And DYRK Kinases | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2013-04-25 | — | — | US | disclosed |
| WO-2013026890-A1 | SUSCEPTIBILITY TO SELECTIVE CDK9 INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2013-02-28 | — | — | WO | disclosed |
| US-7704961-B2 | Avermectins and avermectin monosacharides substituted in the 4′-and 4″ position having pesticidal properties | MERIAL LIMITED (US) | 2010-04-27 | — | — | US | disclosed |
| US-7704961-B2 | Avermectins and avermectin monosacharides substituted in the 4′-and 4″ position having pesticidal properties | MERIAL LIMITED (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080194498-A1 | Miticides and nematocides well-tolerated by livestock and domestic animals; effective against pesticide-resistant pests; protection for plant propagation material | MERIAL, INC. | 2008-08-14 | — | — | US | disclosed |
| US-20080194498-A1 | Miticides and nematocides well-tolerated by livestock and domestic animals; effective against pesticide-resistant pests; protection for plant propagation material | MERIAL, INC. | 2008-08-14 | — | — | US | disclosed |
| EP-1073407-A1 | HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE ORQUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES | L'OREAL (FR) | 2001-02-07 | — | — | EP | disclosed |
| EP-1056434-A1 | DYEING METHOD USING A SPECIFIC CATIONIC DERIVATIVE AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE | L'OREAL (FR) | 2000-12-06 | — | — | EP | disclosed |
| WO-2000038640-A1 | HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000038639-A1 | DYEING METHOD USING A SPECIFIC CATIONIC DERIVATIVE AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| US-6077320-A | DYEING HAIR WITHOUT AN OXIDIZER BY REACTION OF HAIR DYE WITH A PRIMARY OR SECONDARY AMINE-FUNCTIONAL COMPOUND IN THE DYE MEDIUM | L'OREAL (FR) | 2000-06-20 | — | — | US | disclosed |
| EP-0847749-B1 | Use of diiminoisoindoline or 3-aminoisoindolone derivatives for the dyeing of keratinic fibers and compositions containing them | OREAL (FR) | 1999-12-01 | — | — | EP | disclosed |
| EP-0847749-A1 | Use of diiminoisoindoline or 3-aminoisoindolone derivatives for the dyeing of keratinic fibers and compositions containing them | L'OREAL (FR) | 1998-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | CASP3 1022/4885TTR 3199/4885CES1 3158/4885 |
| US-20080194498-A1 | Miticides and nematocides well-tolerated by livestock and domestic animals; effective against pesticide-resistant pests; protection for plant propagation material | ZYX, MTX1, CHRM1 | CASP3 86/4885TTR 1837/4885CES1 198/4885 |
| US-20130102627-A1 | Acridines As Inhibitors Of Haspin And DYRK Kinases | HASPIN, MAP3K6, DAPK2 | CASP3 4039/4885TTR 4565/4885CES1 2843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.