Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208749 | 0.86 | CCR2 (0.45) | CHRM4OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL206822 | 0.81 | OPRM1 (0.47) | OPRM1OPRL1 | |
| SCHEMBL206307 | 0.80 | OPRM1 (0.52) | CHRM4OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL4084332 | 0.79 | OPRM1 (0.43) | OPRM1OPRL1CCR2KCNH2 | |
| SCHEMBL206135 | 0.74 | OPRM1 (0.62) | OPRM1OPRL1 | |
| SCHEMBL5157641 | 0.72 | OPRM1 (0.43) | CHRM4OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL208760 | 0.70 | SMYD3 (0.48) | OPRM1OPRL1CCR2KCNH2SMYD3 | |
| SCHEMBL207647 | 0.68 | KDM4E (0.46) | — | |
| SCHEMBL206119 | 0.67 | OPRM1 (0.43) | OPRM1OPRL1CCR2KCNH2SMYD3 | |
| SCHEMBL205707 | 0.65 | FAAH (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007536323-A | — | — | 2007-12-13 | — | — | JP | claimed |
| EP-1745010-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-01-24 | — | — | EP | claimed |
| WO-2005110974-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | claimed |