Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162314 | 0.84 | CCR5 (0.38) | MEN1KMT2ATACR1SIGMAR1 | |
| SCHEMBL5164050 | 0.84 | CCR5 (0.38) | MEN1KMT2ASMN1; SMN2LMNAOPRM1 | |
| Hydrochloric Acid SCHEMBL5846847 | 0.83 | CCR5 (0.37) | MEN1KMT2ATACR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL6937462 | 0.83 | DPP4 (0.37) | TACR1OPRL1 | |
| SCHEMBL6936762 | 0.83 | SLC6A9 (0.39) | SMN1; SMN2LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL6939728 | 0.83 | ALDH1A1 (0.40) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6936254 | 0.82 | C3AR1 (0.37) | MEN1KMT2ASMN1; SMN2LMNAOPRM1 | |
| Hydrochloric Acid SCHEMBL7741182 | 0.82 | OPRL1 (0.39) | SMN1; SMN2LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL6939842 | 0.81 | MEN1 (0.37) | MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL5164176 | 0.80 | SLC6A2 (0.44) | MEN1KMT2ASIGMAR1LMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406857-B1 | SUBSTITUTED 1-ARYL-BUT-3-ENYLAMINE AND 1-ARYL-BUT-2-ENYLAMINE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2007-02-21 | — | — | EP | disclosed |