Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.33 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.33 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207100 | 0.83 | NPSR1 (0.43) | MEN1KMT2AALDH1A1TP53MAPT | |
| SCHEMBL206590 | 0.81 | MEN1 (0.47) | NAMPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL205784 | 0.79 | MEN1 (0.49) | NAMPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL205169 | 0.78 | SIGMAR1 (0.41) | CNR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL207488 | 0.74 | MEN1 (0.47) | MEN1KMT2AALDH1A1TP53MAPT | |
| SCHEMBL5158010 | 0.74 | OPRM1 (0.40) | CNR1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL5158031 | 0.73 | KMT2A (0.52) | NAMPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL5160624 | 0.71 | LMNA (0.43) | MEN1KMT2AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL205873 | 0.70 | UTS2R (0.43) | KMT2APOLB | |
| SCHEMBL205853 | 0.70 | HPGD (0.40) | MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005110974-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |