Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14465824 | 0.80 | RAB9A (0.42) | RAB9AKDM4ESMN1; SMN2NPC1TNKS2 | |
| SCHEMBL29977924 | 0.80 | RAB9A (0.42) | RAB9AKDM4ESMN1; SMN2NPC1TNKS2 | |
| SCHEMBL2180069 | 0.79 | RAB9A (0.63) | RAB9AALDH1A1MAPK1MAPTKDM4E | |
| SCHEMBL14644025 | 0.78 | LMNA (0.42) | RAB9AALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL19503489 | 0.78 | MAPT (0.48) | ALDH1A1MAPTKDM4ERECQLSMN1; SMN2 | |
| SCHEMBL9380265 | 0.77 | MEN1 (0.48) | RAB9AALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29468686 | 0.77 | MEN1 (0.48) | RAB9AALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9673902 | 0.76 | MAPT (0.63) | RAB9ACYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL6724720 | 0.76 | AAK1 (0.37) | RAB9ACYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL9379043 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765348-A2 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M Innovative Properties Company (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006028545-A2 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |