Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976846 | 0.83 | CES2 (0.60) | RAB9ANPC1ERCC5FEN1ALDH1A1 | |
| SCHEMBL29560924 | 0.83 | CES2 (0.60) | RAB9ANPC1ERCC5FEN1ALDH1A1 | |
| Phthalic Acid SCHEMBL28043206 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPK1LMNAKDM4EHPGD | |
| SCHEMBL2837238 | 0.74 | ERCC5 (0.58) | RAB9ANPC1ERCC5FEN1ALDH1A1 | |
| Phenyl Ethanol SCHEMBL28552574 | 0.73 | LMNA (0.54) | ALDH1A1MAPK1HIF1ACES2CES1 | |
| Phenyl Ethanol SCHEMBL27536420 | 0.73 | LMNA (0.54) | ALDH1A1MAPK1HIF1ALMNAKDM4E | |
| SCHEMBL11650545 | 0.73 | ERCC5 (0.53) | RAB9ANPC1ERCC5FEN1GPR139 | |
| Hydrochloric Acid SCHEMBL30461901 | 0.72 | ERCC5 (0.56) | RAB9ANPC1ERCC5FEN1ALDH1A1 | |
| Water SCHEMBL7994046 | 0.72 | ERCC5 (0.56) | RAB9ANPC1ERCC5FEN1ALDH1A1 | |
| Phenacyl Chloride SCHEMBL5158969 | 0.72 | ALDH1A1 (0.59) | ALDH1A1MAPK1HIF1ACES1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747224-A1 | COMPLEXES OF RUTHENIUM WITH 2-(AMINOMETHYL)PYRIDINES AND PHOSPHINES, THEIR PREPARATION AND USE AS CATALYSTS | Universita' Degli Studi di Udine (IT) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005105819-A1 | COMPLEXES OF RUTHENIUM WITH 2-(AMINOMETHYL)PYRIDINES AND PHOSPHINES, THEIR PREPARATION AND USE AS CATALYSTS | UNIVERSITA' DEGLI STUDI DI UDINE (IT) | 2005-11-10 | — | — | WO | disclosed |