Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.60 |
| ▸ | CES1 | P23141 | 1/20 | 0.60 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.60 |
| ▸ | FEN1 | P39748 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560924 | 1.00 | CES2 (0.60) | CES2CES1ERCC5FEN1ALDH1A1 | |
| SCHEMBL11737575 | 0.85 | ALDH1A1 (0.61) | CES2CES1ERCC5FEN1ALDH1A1 | |
| SCHEMBL15979733 | 0.84 | CES2 (0.62) | CES2CES1ERCC5FEN1ALDH1A1 | |
| SCHEMBL29987169 | 0.84 | ERCC5 (0.74) | CES2CES1ERCC5FEN1ALDH1A1 | |
| Phenyl Ethanol SCHEMBL5158975 | 0.83 | RAB9A (0.51) | CES2CES1ERCC5FEN1ALDH1A1 | |
| SCHEMBL8676987 | 0.83 | ERCC5 (0.56) | CES2CES1ERCC5FEN1ALDH1A1 | |
| SCHEMBL3142115 | 0.83 | ERCC5 (0.62) | CES2CES1ERCC5FEN1ALDH1A1 | |
| SCHEMBL1266557 | 0.82 | CES2 (0.60) | CES2CES1ERCC5FEN1ALDH1A1 | |
| SCHEMBL2848421 | 0.82 | CES2 (0.60) | CES2CES1ERCC5FEN1ALDH1A1 | |
| SCHEMBL27653603 | 0.81 | KLKB1 (0.49) | CES2CES1ERCC5FEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109759-B | Carbonyl reductase LsCR mutant, engineering bacterium and application thereof in preparation of chiral alcohol by asymmetric reduction of carbonyl compound | 浙江工业大学 | 2024-05-03 | — | — | CN | claimed |
| CN-111253233-B | Transposition method of acetophenone isomer | 浙江禾本科技股份有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-115109759-A | Carbonyl reductase LsCR mutant, engineering bacteria and application in preparation of chiral alcohol by asymmetrically reducing carbonyl compound | 浙江工业大学 | 2022-09-27 | — | — | CN | claimed |
| CN-113307721-B | Recovery and utilization of 2, 4-dichloroacetophenone isomer 2, 6-dichloroacetophenone | 浙江禾本科技股份有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-113307721-A | Recovery and utilization of 2, 4-dichloroacetophenone isomer 2, 6-dichloroacetophenone | 浙江禾本科技股份有限公司 | 2021-08-27 | — | — | CN | claimed |
| CN-108445121-B | Method for separating and measuring 2, 4-dichloroacetophenone and 2, 6-dichloroacetophenone isomers by gas chromatography | 常州市盛辉药业有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-112299974-A | Method for synthesizing 2, 4-dichloroacetophenone by recycling acetophenone crystallization waste | 宁夏瑞泰科技股份有限公司 | 2021-02-02 | — | — | CN | claimed |
| CN-111253233-A | Transposition method of acetophenone isomer | 浙江禾本科技股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-105254586-B | Sulfur heterocyclic ring chalcone derivative and its preparation method and application | 郑州大学 | 2017-06-30 | — | — | CN | claimed |
| CN-105254586-A | Sulfur-containing heterocyclic chalcone derivatives, preparation method and applications | UNIV ZHENGZHOU | 2016-01-20 | — | — | CN | claimed |
| EP-3881048-B1 | DEVICE FOR REMOVING VOLATILE ORGANIC COMPOUNDS | LETAT FRANCAIS REPRESENTE PAR LE MINI DE LINTERIEUR (FR) | 2026-05-06 | — | — | EP | disclosed |
| EP-4069680-B1 | PROCESS FOR SYNTHESIS OF A 2-(5-ISOXAZOLYL)-PHENOL | FMC CORP (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12516045-B2 | Process for synthesis of a 2-thioalkyl pyrimidine | FMC CORPORATION (US) | 2026-01-06 | — | — | US | disclosed |
| US-12291525-B2 | Process for synthesis of a 2-(5-isoxazolyl)-phenol | FMC CORPORATION (US) | 2025-05-06 | — | — | US | disclosed |
| CN-118026949-A | Thiazole histone deacetylase inhibitor and preparation method and application thereof | 济南大学 | 2024-05-14 | — | — | CN | disclosed |
| EP-0012850-B1 | PROCESS FOR THE PREPARATION OF KETONES BY REACTING CARBOXYLIC-ACID HALIDES WITH ALKYL ALUMINIUM COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-25 | — | — | EP | disclosed |
| US-4282145-A | Process for the preparation of azetidines | GIST-BROCADES N.V. (NL) | 1981-08-04 | — | — | US | disclosed |
| US-4266066-A | FROM CARBOXYLIC ACYL HALIDE AND ALUMINUM ALKYL COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |
| US-3960961-A | 4'-Fluoro-4-{[4-(phenyl)cyclohexyl]amino}butyrophenones and the salts thereof | THE UPJOHN COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
| US-3932338-A | POLYOLEFINS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12291525-B2 | Process for synthesis of a 2-(5-isoxazolyl)-phenol | CYP4F11, CYP2F1, CYP1A2 | CES2 2149/4885CES1 2257/4885ERCC5 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.