Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161307 | 0.90 | TUBB4A (0.46) | KDM4EALDH1A1MAPTAHRPTGS2 | |
| SCHEMBL15330440 | 0.85 | MTNR1A (0.49) | KDM4EALDH1A1MAPTAHRERN1 | |
| SCHEMBL5159722 | 0.82 | MAOA (0.43) | KIF11KDM4EALDH1A1MAPTMAOA | |
| SCHEMBL5157844 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1MAPTMAOAAHR | |
| SCHEMBL15332438 | 0.80 | PTGS2 (0.58) | KDM4EALDH1A1MAPTAHRPTGS2 | |
| SCHEMBL28402701 | 0.79 | MTNR1A (0.55) | KDM4EALDH1A1MAPTAHRPTGS2 | |
| SCHEMBL15331960 | 0.77 | CCNB2 (0.50) | KIF11MAPTAHRPTGS2MAPK13 | |
| SCHEMBL5161888 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1MAPTAHRPTGS2 | |
| SCHEMBL15332111 | 0.75 | KDM4E (0.44) | KIF11KDM4EALDH1A1MAPTPTGS2 | |
| SCHEMBL5158471 | 0.75 | MAOA (0.45) | KDM4EALDH1A1MAPTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746087-A1 | Derivates of 3-indolylmethylene having cytostatic properties | Universitaet Regensburg (DE) | 2007-01-24 | — | — | EP | disclosed |