Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5159727

COCCNC(=O)Cc1cc(O)ccc1N.N

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.49
KDM4E B2RXH2 2/20 0.48
GLA P06280 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
HPGD P15428 6/20 0.42
EGFR P00533 1/20 0.41
SPR P35270 2/20 0.39
PTGER4 P35408 1/20 0.39
POLB P06746 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TSHR P16473 1/20 0.39
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5159732 0.99 CA2 (0.50) CA2KDM4EGLAL3MBTL1HPGD
SCHEMBL5159800 0.91 ALDH1A1 (0.47) CA2KDM4EGLAL3MBTL1HPGD
SCHEMBL5161617 0.83 TSHR (0.41) CA2KDM4EL3MBTL1HPGDEGFR
SCHEMBL5160286 0.81 PDK2 (0.38) CA2EGFRCYP1A2TSHR
SCHEMBL5164514 0.81 CNR2 (0.39) KDM4EEGFR
SCHEMBL5163009 0.81 CA1 (0.49) CA2KDM4EHPGDEGFRCYP1A2
SCHEMBL5162190 0.80 MEN1 (0.40) HPGDEGFR
SCHEMBL5163737 0.79 PTGS2 (0.42) CA2L3MBTL1HPGDEGFR
SCHEMBL5160950 0.78 KDM4E (0.50) CA2KDM4EGLAL3MBTL1HPGD
SCHEMBL5086747 0.77 CA2 (0.67) CA2KDM4EGLAL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1762218-A1 4-aminophenol derivatives and colorants comprising these compounds Wella Aktiengesellschaft (DE) 2007-03-14 EP disclosed
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed