SCHEMBL5159732

SCHEMBL5159732

COCCNC(=O)Cc1cc(O)ccc1N

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.50
KDM4E B2RXH2 2/20 0.49
GLA P06280 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HPGD P15428 6/20 0.43
EGFR P00533 1/20 0.41
SPR P35270 2/20 0.40
PTGER4 P35408 1/20 0.40
POLB P06746 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TSHR P16473 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL5159727 0.99 CA2 (0.49) CA2KDM4EGLAL3MBTL1HPGD
SCHEMBL5159800 0.92 ALDH1A1 (0.47) CA2KDM4EGLAL3MBTL1HPGD
SCHEMBL5161617 0.84 TSHR (0.41) CA2KDM4EL3MBTL1HPGDEGFR
SCHEMBL5160286 0.82 PDK2 (0.38) CA2EGFRCYP1A2TSHR
SCHEMBL5164514 0.82 CNR2 (0.39) KDM4EEGFR
SCHEMBL5163009 0.82 CA1 (0.49) CA2KDM4EHPGDEGFRCYP1A2
SCHEMBL5162190 0.81 MEN1 (0.40) HPGDEGFR
SCHEMBL5163737 0.80 PTGS2 (0.42) CA2L3MBTL1HPGDEGFR
SCHEMBL5160950 0.79 KDM4E (0.50) CA2KDM4EGLAL3MBTL1HPGD
SCHEMBL5086747 0.78 CA2 (0.67) CA2KDM4EGLAL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070067922-A1 4-Aminophenol derivatives and colorants comprising these compounds PROCTER & GAMBLE COMPANY, THE 2007-03-29 US claimed
EP-1762218-A1 4-aminophenol derivatives and colorants comprising these compounds Wella Aktiengesellschaft (DE) 2007-03-14 EP claimed
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO claimed
US-20070067922-A1 4-Aminophenol derivatives and colorants comprising these compounds PROCTER & GAMBLE COMPANY, THE 2007-03-29 US disclosed
EP-1762218-A1 4-aminophenol derivatives and colorants comprising these compounds Wella Aktiengesellschaft (DE) 2007-03-14 EP disclosed
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070067922-A1 4-Aminophenol derivatives and colorants comprising these compounds KRT18, S100A4, CKAP4 CA2 1440/4885KDM4E 251/4885GLA 352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.