Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.30 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.30 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.30 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.30 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.30 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.30 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.30 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.30 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158451 | 0.95 | DHODH (0.35) | DHODHTRPV1CCR2NR1H4 | |
| SCHEMBL4083007 | 0.79 | DHODH (0.45) | EPHX2DHODH | |
| SCHEMBL206128 | 0.78 | SSTR1 (0.39) | EPHX2OPRM1OPRL1CCR2NR1H4 | |
| SCHEMBL206834 | 0.76 | DHODH (0.48) | EPHX2DHODH | |
| SCHEMBL206533 | 0.76 | CYP2C9 (0.42) | CCR2NR1H4 | |
| SCHEMBL207910 | 0.76 | OPRM1 (0.50) | EPHX2OPRM1OPRL1 | |
| SCHEMBL206685 | 0.76 | EPHX2 (0.43) | EPHX2 | |
| SCHEMBL205814 | 0.76 | LMNA (0.44) | EPHX2DHODH | |
| SCHEMBL5160034 | 0.76 | DHODH (0.40) | EPHX2DHODHCCR4 | |
| SCHEMBL207581 | 0.75 | POLB (0.46) | EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007536323-A | — | — | 2007-12-13 | — | — | JP | claimed |
| EP-1745010-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-01-24 | — | — | EP | claimed |
| WO-2005110974-A1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | claimed |