Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163685 | 0.87 | FKBP1A (0.41) | RAB9AHSD17B10LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9486009 | 0.81 | RAB9A (0.42) | RAB9AHSD17B10LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL8823436 | 0.72 | RAB9A (0.35) | RAB9AHSD17B10LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL7398963 | 0.72 | ACE (0.39) | RAB9AHSD17B10LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL21371448 | 0.72 | RAB9A (0.42) | RAB9AHSD17B10LMNASMN1; SMN2ACE | |
| SCHEMBL14104056 | 0.70 | HSD17B10 (0.44) | RAB9AHSD17B10LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL17053427 | 0.70 | HSD17B10 (0.44) | RAB9AHSD17B10LMNACYP2C19ACE | |
| SCHEMBL1955287 | 0.69 | ACE (0.45) | RAB9AHSD17B10LMNACYP2C19ACE | |
| SCHEMBL13101915 | 0.69 | ACE (0.45) | RAB9AHSD17B10LMNACYP2C19ACE | |
| SCHEMBL10110614 | 0.68 | RAB9A (0.43) | RAB9AHSD17B10LMNACYP2C19ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | RAB9A 1194/4885HSD17B10 3097/4885LMNA 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.