Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586902 | 0.77 | HTR2A (0.52) | HTR2AHRH1KDM4EALDH1A1TDP1 | |
| SCHEMBL674996 | 0.77 | CHRNA7 (0.59) | HTR2AHRH1KDM4EALDH1A1TDP1 | |
| SCHEMBL25638432 | 0.76 | KDM4E (0.45) | HTR2AHRH1KDM4EALDH1A1TDP1 | |
| Water SCHEMBL28355612 | 0.74 | CHRNA7 (0.56) | HTR2AHRH1KDM4EALDH1A1TDP1 | |
| SCHEMBL774509 | 0.74 | MEN1 (0.55) | HTR2AHRH1KDM4EALDH1A1TDP1 | |
| SCHEMBL366705 | 0.74 | MEN1 (0.55) | HTR2AHRH1KDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL11332719 | 0.74 | CHRNA7 (0.56) | HTR2AHRH1KDM4EALDH1A1TDP1 | |
| SCHEMBL735155 | 0.74 | MEN1 (0.55) | HTR2AHRH1KDM4EALDH1A1TDP1 | |
| SCHEMBL9814876 | 0.74 | CHRNA7 (0.64) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL3356477 | 0.74 | HTR2A (0.50) | HTR2AHRH1KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006031411-A2 | A CONDUCTIVE LITHOGRAPHIC POLYMER MIXTURE AND METHOD OF MAKING DEVICES USING SAME | INTEL CORPORATION (US) | 2006-03-23 | — | — | WO | claimed |
| EP-3374344-B1 | IMPROVED PROCESS FOR THE REDUCTIVE AMINATION OF HALOGEN-CONTAINING SUBSTRATES | TAMINCO BV (BE) | 2023-10-04 | — | — | EP | disclosed |
| US-11691136-B2 | Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst | MITSUI CHEMICALS, INC. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11691136-B2 | Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst | MITSUI CHEMICALS, INC. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-10766972-B2 | Modified conjugated diene-based polymer and method for producing the same, and modified conjugated diene-based polymer composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-09-08 | — | — | US | disclosed |
| US-20200222886-A1 | OLEFIN OLIGOMERIZATION CATALYST AND METHOD FOR PRODUCING OLEFIN OLIGOMER IN THE PRESENCE OF THE SAME CATALYST | MITSUI CHEMICALS, INC. (JP) | 2020-07-16 | — | — | US | disclosed |
| US-10544087-B2 | Process for the reductive amination of halogen-containing substrates | TAMINCO BVBA (BE) | 2020-01-28 | — | — | US | disclosed |
| US-10464879-B2 | Process for the reductive amination of halogen-containing substrates | TAMINCO BVBA (BE) | 2019-11-05 | — | — | US | disclosed |
| EP-3260476-B1 | MODIFIED CONJUGATED DIENE-BASED POLYMER, MANUFACTURING METHOD THEREOF, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPOSITION | ASAHI CHEMICAL IND (JP) | 2019-05-08 | — | — | EP | disclosed |
| EP-3374344-A1 | IMPROVED PROCESS FOR THE REDUCTIVE AMINATION OF HALOGEN-CONTAINING SUBSTRATES | Taminco bvba (BE) | 2018-09-19 | — | — | EP | disclosed |
| EP-1043306-B1 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and use | GRUENENTHAL GMBH (DE) | 2004-03-31 | — | — | EP | disclosed |
| US-20030008859-A1 | Use of substituted 4-amino-1-phenylbutan-2-ol compounds as medicaments | GRUENENTHAL GMBH (DE) | 2003-01-09 | — | — | US | disclosed |
| EP-1253917-A2 | USE OF SUBSTITUTED 4-AMINO-1-PHENYLBUTAN-2-OL COMPOUNDS AS MEDICAMENTS | Grünenthal GmbH (DE) | 2002-11-06 | — | — | EP | disclosed |
| US-6410790-B1 | ANALGESICS | GRUENENTHAL GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| WO-2001047506-A2 | USE OF SUBSTITUTED 4-AMINO-1-PHENYLBUTAN-2-OL COMPOUNDS AS MEDICAMENTS | Grünenthal GmbH (DE) | 2001-07-05 | — | — | WO | disclosed |
| EP-1043307-A2 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | Grünenthal GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| EP-1043306-A2 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and use | Grünenthal GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| US-4886720-A | Photosensitive medium having a styryl charge transport material | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1989-12-12 | — | — | US | disclosed |
| US-4423247-A | AMINOALKYLATION, NONCATALYTIC REACTION | BASF AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |
| US-4181661-A | SCHIZOPHRENIA, PSYCHOLOGICAL DISORDERS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008859-A1 | Use of substituted 4-amino-1-phenylbutan-2-ol compounds as medicaments | OPRL1, OPRM1, OPRK1 | HTR2A 356/4885HRH1 224/4885KDM4E 4401/4885 |
| US-20200222886-A1 | OLEFIN OLIGOMERIZATION CATALYST AND METHOD FOR PRODUCING OLEFIN OLIGOMER IN THE PRESENCE OF THE SAME CATALYST | OXER1, COG6, CBR1 | HTR2A 1012/4885HRH1 148/4885KDM4E 3804/4885 |
| US-11691136-B2 | Olefin oligomerization catalyst and method for producing olefin oligomer in the presence of the same catalyst | OXER1, COG6, CBR1 | HTR2A 1012/4885HRH1 148/4885KDM4E 3804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.