SCHEMBL735155

SCHEMBL735155

C[C@H](c1ccccc1)N(C)C

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
MAPT P10636 1/20 0.55
CYP2C9 P11712 1/20 0.55
KMT2A Q03164 1/20 0.55
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
HTR2A P28223 3/20 0.50
HRH1 P35367 3/20 0.50
ALOX5 P09917 1/20 0.48
MTOR P42345 1/20 0.47
AOC3 Q16853 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
ACHE P22303 1/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
TAAR1 Q96RJ0 2/20 0.42
RIPK1 Q13546 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2C P18825 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366705 1.00 MEN1 (0.55) MEN1MAPTCYP2C9KMT2AKDM4E
SCHEMBL774509 1.00 MEN1 (0.55) MEN1MAPTCYP2C9KMT2AKDM4E
Iodide SCHEMBL27880620 0.97 MEN1 (0.53) MEN1MAPTCYP2C9KMT2AKDM4E
Water SCHEMBL9747158 0.97 MEN1 (0.53) MEN1MAPTCYP2C9KMT2AKDM4E
Bromide SCHEMBL3879339 0.97 MEN1 (0.53) MEN1MAPTCYP2C9KMT2AKDM4E
Bromide SCHEMBL5789798 0.97 MEN1 (0.53) MEN1MAPTCYP2C9KMT2AKDM4E
SCHEMBL8405249 0.97 MEN1 (0.53) MEN1MAPTCYP2C9KMT2AKDM4E
Hydrochloric Acid SCHEMBL27284036 0.97 MEN1 (0.59) MEN1MAPTCYP2C9KMT2AKDM4E
Hydrochloric Acid SCHEMBL28035064 0.95 MEN1 (0.57) MEN1MAPTCYP2C9KMT2AKDM4E
Hydrochloric Acid SCHEMBL28211053 0.95 MEN1 (0.57) MEN1MAPTCYP2C9KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760750-B1 Process for preparing levoketoconazole NURAY CHEMICALS PRIVATE LIMITED (IN) 2023-09-19 US claimed
CN-115093392-A Preparation method of R-lipoic acid 苏州富士莱医药股份有限公司 2022-09-23 CN claimed
US-8853390-B2 Processes for preparing 1,2-substituted cyclopropyl derivatives ABBVIE INC. (US) 2014-10-07 US claimed
WO-2012037258-A1 PROCESSES FOR PREPARING 1,2-SUBSTITUTED CYCLOPROPYL DERIVATIVES ABBOTT LABORATORIES (US) 2012-03-22 WO claimed
US-20120071651-A1 Processes for Preparing 1,2-Substituted Cyclopropyl Derivatives ABBOTT LABORATORIES (US) 2012-03-22 US claimed
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS CORN PRODUCTS DEV INC (US) 2026-02-05 US disclosed
EP-4561366-A1 FLAVOR MODIFYING COMPOSITION CORN Products Development Inc. (US) 2025-06-04 EP disclosed
US-20250135005-A1 PROCESSES FOR PREPARING FUNCTIONALIZED CYCLOOCTENES TAMBO INC (US) 2025-05-01 US disclosed
US-20250081996-A1 FLAVOR MODIFYING COMPOSITION PURECIRCLE SDN BHD (MY) 2025-03-13 US disclosed
US-12194100-B2 Processes for preparing functionalized cyclooctenes TAMBO, INC. (US) 2025-01-14 US disclosed
EP-4380375-A1 METHODS FOR THERMALLY INHIBITING STARCH CORN Products Development Inc. (US) 2024-06-12 EP disclosed
WO-2024026450-A1 FLAVOR MODIFYING COMPOSITION CORN PRODUCTS DEVELOPMENT, INC. (US) 2024-02-01 WO disclosed
WO-2006011045-A1 PHOTORACEMIZATION OF 2-TRIFLUOROMETHYL-2H-CHROMENE-3-CARBOXYLIC ACID DERIVATIVES WARNER-LAMBERT COMPANY LLC (US) 2006-02-02 WO disclosed
WO-2006011052-A1 METHOD FOR THE RACEMIZATION OF 2-TRIFLUORO-2H-CHROMENE-3-CARBOXYLIC ACIDS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-02-02 WO disclosed
US-20060020023-A1 Racemization method PHARMACIA & UPJOHN COMPANY LLC 2006-01-26 US disclosed
US-20060016683-A1 Photoracamization method PHARMACIA & UPJOHN COMPANY LLC 2006-01-26 US disclosed
US-20060020022-A1 Enantioselective separation method PHARMACIA & UPJOHN COMPANY LLC 2006-01-26 US disclosed
US-20050043556-A1 2,2'-Bis(triphenylphosphino)biphenyls complexed with a transition metal-diamine complex; highly active and selective hydrogenation catalysts for the hydrogenation of ketones and imines to alcohols and amines, respectively, used as drug intermediates often required in single isomer form; very low loading MALAN CHRISTOPHE GUILLAUME (CH) 2005-02-24 US disclosed
US-20040186298-A1 Novel use of sulfamic acids as resolving agent AVANTIUM INTERNATIONAL B.V. (NL) 2004-09-23 US disclosed
EP-1264814-A1 Resolving agents based on amines Avantium International B.V. (NL) 2002-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS TAS2R42, TAS2R7, TAS2R31 MEN1 2084/4885MAPT 973/4885CYP2C9 1554/4885
US-12194100-B2 Processes for preparing functionalized cyclooctenes PPOX, SCO2, CYCS MEN1 2903/4885MAPT 4086/4885CYP2C9 857/4885
US-20060020023-A1 Racemization method STS, SQLE, HAO2 MEN1 2567/4885MAPT 4565/4885CYP2C9 24/4885
US-20250135005-A1 PROCESSES FOR PREPARING FUNCTIONALIZED CYCLOOCTENES PPOX, SCO2, CYCS MEN1 2903/4885MAPT 4086/4885CYP2C9 857/4885
US-20050043556-A1 2,2'-Bis(triphenylphosphino)biphenyls complexed with a transition metal-diamine complex; highly active and selective hydrogenation catalysts for the hydrogenation of ketones and imines to alcohols and amines, respectively, used as drug intermediates often required in single isomer form; very low loading ADH5, ADH1A, ADH1C MEN1 2180/4885MAPT 2945/4885CYP2C9 42/4885
US-20120071651-A1 Processes for Preparing 1,2-Substituted Cyclopropyl Derivatives HRH3, HRH4, HRH1 MEN1 1009/4885MAPT 2094/4885CYP2C9 425/4885
US-20060016683-A1 Photoracamization method CYP3A43, CRY2, CRY1 MEN1 3263/4885MAPT 2006/4885CYP2C9 29/4885
US-20060020022-A1 Enantioselective separation method SLC7A1, SLC10A1, DHCR7 MEN1 3502/4885MAPT 3454/4885CYP2C9 184/4885
US-11760750-B1 Process for preparing levoketoconazole KHK, KYAT3, PLK3 MEN1 2073/4885MAPT 1668/4885CYP2C9 108/4885
US-20040186298-A1 Novel use of sulfamic acids as resolving agent HAO1, FPR1, DAO MEN1 4130/4885MAPT 4682/4885CYP2C9 2103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.