Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | FABP2 | P12104 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27592778 | 0.78 | ADORA3 (0.43) | ADORA3PPARAPPARG | |
| SCHEMBL3500736 | 0.75 | PPARA (0.68) | ADORA3PPARAPPARGOPRK1MEN1 | |
| SCHEMBL27610937 | 0.72 | POLB (0.44) | ADORA3PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL30490487 | 0.71 | TDP1 (0.50) | PPARAPPARGCYP1A2MAPTCYP2C19 | |
| SCHEMBL11465749 | 0.70 | FFAR1 (0.54) | ADORA3PPARAPPARGOPRK1MEN1 | |
| SCHEMBL14214408 | 0.70 | PPARA (0.47) | ADORA3PPARAPPARGPPARD | |
| SCHEMBL1960387 | 0.70 | PPARG (0.62) | ADORA3PPARAPPARGOPRK1MEN1 | |
| SCHEMBL11073216 | 0.70 | OPRK1 (0.73) | ADORA3PPARAPPARGOPRK1MEN1 | |
| SCHEMBL5162414 | 0.70 | SMN1; SMN2 (0.50) | PPARAPPARGALDH1A1 | |
| SCHEMBL3682632 | 0.69 | CYP1A2 (0.51) | ADORA3PPARAPPARGOPRK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135468-A1 | PYRIDYLOXYALKANOIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-06-14 | — | — | US | disclosed |
| EP-1456174-B1 | PYRIDYLOXYALKANOIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | SYNGENTA LTD (GB) | 2007-02-14 | — | — | EP | disclosed |
| US-7166621-B2 | Pyridyloxyalkanoic acid amide derivatives useful as fungicides | SYNGENTA LIMITED (GB) | 2007-01-23 | — | — | US | disclosed |
| US-20050065032-A1 | Pyridyloxyalkanoic acid amide derivatives useful as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2005-03-24 | — | — | US | disclosed |
| EP-1456174-A1 | PYRIDYLOXYALKANOIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | Syngenta Limited (GB) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003048128-A1 | PYRIDYLOXYALKANOIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065032-A1 | Pyridyloxyalkanoic acid amide derivatives useful as fungicides | DDT, C3AR1, CNPY3 | ADORA3 236/4885PPARA 3107/4885PPARG 3196/4885 |
| US-20070135468-A1 | PYRIDYLOXYALKANOIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | DDT, C3AR1, CBR3 | ADORA3 273/4885PPARA 2796/4885PPARG 2869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.