SCHEMBL5160716

SCHEMBL5160716

NS(=O)(=O)c1ccc(CC2CCCCC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.54
CA1 P00915 11/20 0.51
CA9 Q16790 10/20 0.51
CA7 P43166 7/20 0.51
CA5A P35218 5/20 0.51
CA5B Q9Y2D0 5/20 0.51
CA12 O43570 8/20 0.51
CA14 Q9ULX7 5/20 0.51
CA4 P22748 4/20 0.50
CA6 P23280 4/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
DUSP3 P51452 1/20 0.50
PTPN5 P54829 1/20 0.50
PTPN11 Q06124 1/20 0.50
ATM Q13315 1/20 0.49
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30269786 0.91 CA2 (0.56) CA2CA1CA9CA7CA5A
SCHEMBL27917814 0.83 GBA1 (0.56) CA2CA1CA9CA7CA5A
SCHEMBL16503442 0.82 LTA4H (0.41) CA2KMT2AMEN1HTTSMN1; SMN2
SCHEMBL656154 0.82 KMT2A (0.44) CA2CA1CA9CA7CA12
Hydrochloric Acid SCHEMBL4777109 0.81 GBA1 (0.54) CA2CA1CA9CA7CA5A
SCHEMBL28298613 0.80 MEN1 (0.50) CA2CA1CA9CA7CA12
SCHEMBL8763564 0.80 MEN1 (0.46) CA2CA1CA9CA7CA12
SCHEMBL25510314 0.78 LTA4H (0.43) KMT2AMEN1
SCHEMBL28164104 0.78 CA1 (0.54) CA2CA1CA9CA7CA5A
SCHEMBL26038271 0.77 CA2 (0.55) CA2CA1CA9CA7CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118984699-A Novel compositions 图莱克斯制药公司 2024-11-19 CN disclosed
CN-118647372-A Liquid resin extended release oral naltrexone formulations for the treatment of autism related disorders 阿达瓦克治疗公司 2024-09-13 CN disclosed
EP-2802576-B1 HETEROCYCLIC-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2018-06-27 EP disclosed
EP-2802577-B1 TRIAZOLYL-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2017-03-01 EP disclosed
CN-103314025-B Aqueous cationic polyurethane dispersions 路博润高级材料公司 2016-08-10 CN disclosed
US-20070179211-A1 Energy-curable intaglio printing SUN CHEMICAL CORPORATIN (US) 2007-08-02 US disclosed
EP-1789493-A1 ALIPHATIC POLYESTER RESIN COMPOSITIONS AND SHAPED ARTICLES 3M Innovative Properties Company (US) 2007-05-30 EP disclosed
EP-1751241-A1 ENERGY-CURABLE INTAGLIO PRINTING INKS Sun Chemical Corporation (US) 2007-02-14 EP disclosed
US-7153902-B2 High solids emulsions of elastomeric polymers DOW CORNING CORPORATION (US) 2006-12-26 US disclosed
EP-1406952-B1 HIGH SOLIDS EMULSIONS OF ELASTOMERIC POLYMERS DOW CORNING (US) 2006-10-04 EP disclosed
US-20030109632-A1 High solids emulsions of curable elastomeric polymers DOW CORNING CORPORATION 2003-06-12 US disclosed
US-20030109616-A1 High solids emulsions of silylated elastomeric polymers DOW CORING CORPORATION 2003-06-12 US disclosed
US-20030092811-A1 High solids emulsions of elastomeric polymers DOW CORNING CORPORATION 2003-05-15 US disclosed
US-20030092810-A1 High solids emulsions of silylated elastomeric polymers DOW CORNING CORPORATION 2003-05-15 US disclosed
US-20030088005-A1 High solids emulsions of curable elastomeric polymers DOW CORNING CORPORATION 2003-05-08 US disclosed
WO-2003035759-A1 THERMOPLASTIC SILICONE ELASTOMERS FROM COMPATIBILIZED POLYAMIDE RESINS DOW CORNING CORPORATION (US) 2003-05-01 WO disclosed
WO-2003006533-A1 HIGH SOLIDS EMULSIONS OF ELASTOMERIC POLYMERS DOW CORNING CORPORATION (US) 2003-01-23 WO disclosed
WO-2003006514-A1 HIGH SOLIDS EMULSIONS OF CURABLE ELASTOMERIC POLYMERS DOW CORNING CORPORATION (US) 2003-01-23 WO disclosed
WO-2003006534-A1 HIGH SOLIDS EMULSIONS OF SILYLATED ELASTOMERIC POLYMERS DOW CORNING CORPORATION (US) 2003-01-23 WO disclosed
WO-2002034502-A2 IMPROVED METHOD FOR FORMING INTERNALLY BONDED JOINT STRUCTURES, JOINT STRUCTURES SO FORMED, AND APPARATUS THEREFORE ANDERSEN CORPORATION (US) 2002-05-02 WO disclosed