Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6393615 | 0.84 | GBA1 (0.53) | MEN1KMT2ACA2CA1CA12 | |
| SCHEMBL5160716 | 0.80 | CA2 (0.54) | MEN1KMT2ACA2CA1CA12 | |
| SCHEMBL28343967 | 0.75 | PLAU (0.40) | — | |
| SCHEMBL10347651 | 0.75 | MAOA (0.46) | MEN1KMT2A | |
| SCHEMBL22170191 | 0.73 | PRMT6 (0.49) | SMN1; SMN2 | |
| SCHEMBL1238863 | 0.73 | MEN1 (0.57) | MEN1KMT2ACA2CA1CA12 | |
| SCHEMBL13432911 | 0.73 | HTR6 (0.42) | MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9796363 | 0.73 | PTGS2 (0.42) | CA2CA1CA12CA9CA14 | |
| SCHEMBL13964066 | 0.73 | KMT2A (0.46) | MEN1KMT2ACA2CA1CA12 | |
| SCHEMBL30755238 | 0.72 | CA1 (0.53) | MEN1KMT2ACA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715629-A | AZA-INDAZOLE COMPOUNDS FOR USE IN TENDON AND/OR LIGAMENT INJURIES | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |