Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161578 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1KMT2APOLBSCN5A | |
| SCHEMBL6179708 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1KMT2APOLBSCN5A | |
| SCHEMBL5163745 | 0.79 | HTT (0.48) | SMN1; SMN2ALDH1A1KMT2ATSHRFKBP1A | |
| SCHEMBL71756 | 0.79 | FKBP1A (0.44) | SMN1; SMN2ALDH1A1POLBNPC1HSD17B10 | |
| SCHEMBL5158609 | 0.79 | FKBP1A (0.44) | SMN1; SMN2ALDH1A1POLBNPC1HSD17B10 | |
| SCHEMBL27562911 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KMT2APOLBNPC1 | |
| SCHEMBL4299188 | 0.76 | HSD17B10 (0.42) | SMN1; SMN2HSD17B10KDM4ELMNA | |
| SCHEMBL4299186 | 0.76 | HSD17B10 (0.42) | SMN1; SMN2HSD17B10KDM4ELMNA | |
| SCHEMBL5160904 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1KMT2APOLBCMA1 | |
| SCHEMBL5158933 | 0.72 | HRH3 (0.33) | SMN1; SMN2HRH3FAPCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | SMN1; SMN2 3016/4885ALDH1A1 471/4885HRH3 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.