Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158343 | 0.82 | FKBP1A (0.52) | FKBP1ANPSR1PREPALDH1A1CYP3A4 | |
| SCHEMBL5158304 | 0.79 | SMN1; SMN2 (0.47) | FKBP1APREPALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3578383 | 0.79 | SMN1; SMN2 (0.47) | FKBP1APREPALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL5160942 | 0.79 | SMN1; SMN2 (0.37) | FKBP1ANPSR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11584633 | 0.72 | PRCP (0.68) | PRCPNPSR1PREPKMT2AALDH1A1 | |
| SCHEMBL19182782 | 0.72 | HTT (0.54) | HTTNPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5160189 | 0.71 | FKBP1A (0.46) | HTTPRCPFKBP1ANPSR1PREP | |
| SCHEMBL5160862 | 0.71 | CYP11B1 (0.38) | HTTFKBP1APREPKMT2AALDH1A1 | |
| SCHEMBL13745767 | 0.69 | KMT2A (0.58) | HTTPRCPFKBP1ANPSR1KMT2A | |
| SCHEMBL5494817 | 0.69 | KMT2A (0.58) | HTTPRCPFKBP1ANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | HTT 3765/4885PRCP 4605/4885FKBP1A 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.