Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | IAPP | P10997 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15496005 | 0.89 | GABRA1 (0.52) | ALOX5PTGS2ELANEIAPPPPARG | |
| SCHEMBL27438656 | 0.86 | PRKCI (0.47) | PRKCIELANEGABRA1GABRB2THRB | |
| SCHEMBL31572664 | 0.86 | THRA (0.51) | PTGS2ELANEPPARGPPARATHRA | |
| SCHEMBL4596507 | 0.86 | THRA (0.51) | PTGS2ELANEPPARGPPARATHRA | |
| SCHEMBL28837696 | 0.86 | PPARG (0.54) | ALOX5PTGS2PRKCIELANEIAPP | |
| SCHEMBL10632040 | 0.85 | PPARA (0.41) | ALOX5PTGS2PRKCIELANEPPARG | |
| SCHEMBL28731346 | 0.85 | ALOX5 (0.43) | ALOX5PTGS2PRKCIELANETHRB | |
| SCHEMBL6851060 | 0.83 | THRA (0.49) | PTGS2ELANEPPARGPPARATHRA | |
| SCHEMBL5678227 | 0.83 | ALOX5 (0.51) | ALOX5PTGS2PRKCIELANEIAPP | |
| SCHEMBL27863247 | 0.81 | THRB (0.60) | ALOX5PTGS2PRKCIELANEIAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049442-B2 | REBASE MATERIAL FOR PROSTHESIS AND METHOD FOR THE PRODUCTION THEREOF | KETTENBACH GMBH & CO KG (DE) | 2007-03-07 | — | — | EP | claimed |
| EP-1049442-B1 | REBASE MATERIAL FOR PROSTHESIS AND METHOD FOR THE PRODUCTION THEREOF | KETTENBACH GMBH & CO KG (DE) | 2001-12-19 | — | — | EP | claimed |
| CN-113099718-B | Imidazole/thiol polymerization initiation system | 登士柏希罗纳有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-112839981-B | dental composition | 登士柏德特里有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-112638348-B | Method and composition for stabilizing nanogels and dental compositions produced from nanogels | 登士柏希罗纳有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-113164329-B | Composition and method for antibacterial nanogels and hydrolytically stable antibacterial nanogels for dental compositions | 登士柏希罗纳有限公司 | 2023-10-03 | — | — | CN | disclosed |